NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA

In modern epidemiologic conditions revealing of children under the maximal risk of TB infection is the most important object of pediatric phtisiology. Study object: efficacy enhancement of early TB diagnmostics among children and adolescents in public healthcare system. Methods: a multicenter study...

Full description

Bibliographic Details
Main Authors: V.A. Aksenova, L.А. Barishnikova, N.I. Klevno, E.А. Sokolskaya, Е.N. Dolzhenko, А.М. Shuster, V.А. Martyanov, D.А. Kudlay, N.Yu. Nikolenko, А.А. Kurilla
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2011-07-01
Series:Вопросы современной педиатрии
Online Access:https://vsp.spr-journal.ru/jour/article/view/638
_version_ 1826562133085650944
author V.A. Aksenova
L.А. Barishnikova
N.I. Klevno
E.А. Sokolskaya
Е.N. Dolzhenko
А.М. Shuster
V.А. Martyanov
D.А. Kudlay
N.Yu. Nikolenko
А.А. Kurilla
author_facet V.A. Aksenova
L.А. Barishnikova
N.I. Klevno
E.А. Sokolskaya
Е.N. Dolzhenko
А.М. Shuster
V.А. Martyanov
D.А. Kudlay
N.Yu. Nikolenko
А.А. Kurilla
author_sort V.A. Aksenova
collection DOAJ
description In modern epidemiologic conditions revealing of children under the maximal risk of TB infection is the most important object of pediatric phtisiology. Study object: efficacy enhancement of early TB diagnmostics among children and adolescents in public healthcare system. Methods: a multicenter study was carried out in the city of Moscow, Samara and Ryazan regions. Children and adolescents under high risk of TB infection were included into this study. The study consisted of three phases: first — Diaskintest intracutaneous test assessment in children and adolescents within TB dispensery; second — same procedure performed among children and adolescents not registered in TB despensery but taken care of by a local pediatrician; third — among pupils of secondary complementary education institutions. Results: first phase of the study showed that every second child, registered in TB dispensery due to MTB contamination, which was revealed via traditional diagnostic procedures, receives unreasonable chemoprophylaxis. Among pediatric patients (second phase) TB was diagnosed in 2.3% of total amount of children from this group and among 26.7% of Diaskintestpositive patients. Testing patients in the third phase of the study (pupils of of secondary complementary education institutions) revealed TB infection in 0.6% of tested and in 21.2% among Diaskintest-positive patients. Conclusion: Diaskintest use as a screening method among children helps revealing patients under highest risk of TB infection.Key words: children, tuberculosis, diagnostics, Diaskintest, Mantoux test.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (4): 16–22)
first_indexed 2024-03-12T04:54:14Z
format Article
id doaj.art-d536852149704c408e273a1c87927518
institution Directory Open Access Journal
issn 1682-5527
1682-5535
language English
last_indexed 2025-03-14T09:43:13Z
publishDate 2011-07-01
publisher "Paediatrician" Publishers LLC
record_format Article
series Вопросы современной педиатрии
spelling doaj.art-d536852149704c408e273a1c879275182025-03-02T11:34:01Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352011-07-01104638NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIAV.A. Aksenova0L.А. Barishnikova1N.I. Klevno2E.А. Sokolskaya3Е.N. Dolzhenko4А.М. Shuster5V.А. Martyanov6D.А. Kudlay7N.Yu. Nikolenko8А.А. Kurilla9Scientific-research center of phthisiopulmonology Sechenov First Moscow State Medical University, MoscowSamara regional TB despensaryScientific-research center of phthisiopulmonology Sechenov First Moscow State Medical University, MoscowScientific-research center of phthisiopulmonology Sechenov First Moscow State Medical University, MoscowRyazan regional TB despensaryCC Generium, MoscowCC Lekko, MoscowJSC Farmstandart, MoscowJSC Farmstandart, MoscowCC Lekko, MoscowIn modern epidemiologic conditions revealing of children under the maximal risk of TB infection is the most important object of pediatric phtisiology. Study object: efficacy enhancement of early TB diagnmostics among children and adolescents in public healthcare system. Methods: a multicenter study was carried out in the city of Moscow, Samara and Ryazan regions. Children and adolescents under high risk of TB infection were included into this study. The study consisted of three phases: first — Diaskintest intracutaneous test assessment in children and adolescents within TB dispensery; second — same procedure performed among children and adolescents not registered in TB despensery but taken care of by a local pediatrician; third — among pupils of secondary complementary education institutions. Results: first phase of the study showed that every second child, registered in TB dispensery due to MTB contamination, which was revealed via traditional diagnostic procedures, receives unreasonable chemoprophylaxis. Among pediatric patients (second phase) TB was diagnosed in 2.3% of total amount of children from this group and among 26.7% of Diaskintestpositive patients. Testing patients in the third phase of the study (pupils of of secondary complementary education institutions) revealed TB infection in 0.6% of tested and in 21.2% among Diaskintest-positive patients. Conclusion: Diaskintest use as a screening method among children helps revealing patients under highest risk of TB infection.Key words: children, tuberculosis, diagnostics, Diaskintest, Mantoux test.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (4): 16–22)https://vsp.spr-journal.ru/jour/article/view/638
spellingShingle V.A. Aksenova
L.А. Barishnikova
N.I. Klevno
E.А. Sokolskaya
Е.N. Dolzhenko
А.М. Shuster
V.А. Martyanov
D.А. Kudlay
N.Yu. Nikolenko
А.А. Kurilla
NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA
Вопросы современной педиатрии
title NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA
title_full NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA
title_fullStr NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA
title_full_unstemmed NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA
title_short NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA
title_sort new screening and diagnostic options of various traits of tb infection among children and adolescents in russia
url https://vsp.spr-journal.ru/jour/article/view/638
work_keys_str_mv AT vaaksenova newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia
AT labarishnikova newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia
AT niklevno newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia
AT easokolskaya newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia
AT endolzhenko newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia
AT amshuster newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia
AT vamartyanov newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia
AT dakudlay newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia
AT nyunikolenko newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia
AT aakurilla newscreeninganddiagnosticoptionsofvarioustraitsoftbinfectionamongchildrenandadolescentsinrussia