NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA
In modern epidemiologic conditions revealing of children under the maximal risk of TB infection is the most important object of pediatric phtisiology. Study object: efficacy enhancement of early TB diagnmostics among children and adolescents in public healthcare system. Methods: a multicenter study...
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Format: | Article |
Language: | English |
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"Paediatrician" Publishers LLC
2011-07-01
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Series: | Вопросы современной педиатрии |
Online Access: | https://vsp.spr-journal.ru/jour/article/view/638 |
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author | V.A. Aksenova L.А. Barishnikova N.I. Klevno E.А. Sokolskaya Е.N. Dolzhenko А.М. Shuster V.А. Martyanov D.А. Kudlay N.Yu. Nikolenko А.А. Kurilla |
author_facet | V.A. Aksenova L.А. Barishnikova N.I. Klevno E.А. Sokolskaya Е.N. Dolzhenko А.М. Shuster V.А. Martyanov D.А. Kudlay N.Yu. Nikolenko А.А. Kurilla |
author_sort | V.A. Aksenova |
collection | DOAJ |
description | In modern epidemiologic conditions revealing of children under the maximal risk of TB infection is the most important object of pediatric phtisiology. Study object: efficacy enhancement of early TB diagnmostics among children and adolescents in public healthcare system. Methods: a multicenter study was carried out in the city of Moscow, Samara and Ryazan regions. Children and adolescents under high risk of TB infection were included into this study. The study consisted of three phases: first — Diaskintest intracutaneous test assessment in children and adolescents within TB dispensery; second — same procedure performed among children and adolescents not registered in TB despensery but taken care of by a local pediatrician; third — among pupils of secondary complementary education institutions. Results: first phase of the study showed that every second child, registered in TB dispensery due to MTB contamination, which was revealed via traditional diagnostic procedures, receives unreasonable chemoprophylaxis. Among pediatric patients (second phase) TB was diagnosed in 2.3% of total amount of children from this group and among 26.7% of Diaskintestpositive patients. Testing patients in the third phase of the study (pupils of of secondary complementary education institutions) revealed TB infection in 0.6% of tested and in 21.2% among Diaskintest-positive patients. Conclusion: Diaskintest use as a screening method among children helps revealing patients under highest risk of TB infection.Key words: children, tuberculosis, diagnostics, Diaskintest, Mantoux test.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (4): 16–22) |
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institution | Directory Open Access Journal |
issn | 1682-5527 1682-5535 |
language | English |
last_indexed | 2025-03-14T09:43:13Z |
publishDate | 2011-07-01 |
publisher | "Paediatrician" Publishers LLC |
record_format | Article |
series | Вопросы современной педиатрии |
spelling | doaj.art-d536852149704c408e273a1c879275182025-03-02T11:34:01Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352011-07-01104638NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIAV.A. Aksenova0L.А. Barishnikova1N.I. Klevno2E.А. Sokolskaya3Е.N. Dolzhenko4А.М. Shuster5V.А. Martyanov6D.А. Kudlay7N.Yu. Nikolenko8А.А. Kurilla9Scientific-research center of phthisiopulmonology Sechenov First Moscow State Medical University, MoscowSamara regional TB despensaryScientific-research center of phthisiopulmonology Sechenov First Moscow State Medical University, MoscowScientific-research center of phthisiopulmonology Sechenov First Moscow State Medical University, MoscowRyazan regional TB despensaryCC Generium, MoscowCC Lekko, MoscowJSC Farmstandart, MoscowJSC Farmstandart, MoscowCC Lekko, MoscowIn modern epidemiologic conditions revealing of children under the maximal risk of TB infection is the most important object of pediatric phtisiology. Study object: efficacy enhancement of early TB diagnmostics among children and adolescents in public healthcare system. Methods: a multicenter study was carried out in the city of Moscow, Samara and Ryazan regions. Children and adolescents under high risk of TB infection were included into this study. The study consisted of three phases: first — Diaskintest intracutaneous test assessment in children and adolescents within TB dispensery; second — same procedure performed among children and adolescents not registered in TB despensery but taken care of by a local pediatrician; third — among pupils of secondary complementary education institutions. Results: first phase of the study showed that every second child, registered in TB dispensery due to MTB contamination, which was revealed via traditional diagnostic procedures, receives unreasonable chemoprophylaxis. Among pediatric patients (second phase) TB was diagnosed in 2.3% of total amount of children from this group and among 26.7% of Diaskintestpositive patients. Testing patients in the third phase of the study (pupils of of secondary complementary education institutions) revealed TB infection in 0.6% of tested and in 21.2% among Diaskintest-positive patients. Conclusion: Diaskintest use as a screening method among children helps revealing patients under highest risk of TB infection.Key words: children, tuberculosis, diagnostics, Diaskintest, Mantoux test.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (4): 16–22)https://vsp.spr-journal.ru/jour/article/view/638 |
spellingShingle | V.A. Aksenova L.А. Barishnikova N.I. Klevno E.А. Sokolskaya Е.N. Dolzhenko А.М. Shuster V.А. Martyanov D.А. Kudlay N.Yu. Nikolenko А.А. Kurilla NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA Вопросы современной педиатрии |
title | NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA |
title_full | NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA |
title_fullStr | NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA |
title_full_unstemmed | NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA |
title_short | NEW SCREENING AND DIAGNOSTIC OPTIONS OF VARIOUS TRAITS OF TB INFECTION AMONG CHILDREN AND ADOLESCENTS IN RUSSIA |
title_sort | new screening and diagnostic options of various traits of tb infection among children and adolescents in russia |
url | https://vsp.spr-journal.ru/jour/article/view/638 |
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