From NAFLD to Chronic Liver Diseases. Assessment of Liver Fibrosis through Non-Invasive Methods before Liver Transplantation: Can We Rely on Them?
Chronic liver injury and subsequent liver fibrosis are usually a slow process without any specific or no clinical signs, resulting in pathological conditions with a poor chance of improvement through medical and surgical treatment, which if not promptly recognized, often lead to a liver transplant a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-05-01
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| Series: | Transplantology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-3943/4/2/8 |
| _version_ | 1797592466778488832 |
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| author | Pasquale Auricchio Michele Finotti |
| author_facet | Pasquale Auricchio Michele Finotti |
| author_sort | Pasquale Auricchio |
| collection | DOAJ |
| description | Chronic liver injury and subsequent liver fibrosis are usually a slow process without any specific or no clinical signs, resulting in pathological conditions with a poor chance of improvement through medical and surgical treatment, which if not promptly recognized, often lead to a liver transplant as the only therapeutic option. On the other hand, screening and follow-up are hard to establish in large populations using regularly invasive methods such as biopsies and other expensive diagnostic tools due to cost and a lack of adequate specificity and sensibility. In the last few years, a large variety of serological and radiological tests have been proposed to assess liver fibrosis. In this review, we will consider the most commonly used scores to evaluate liver fibrosis, with a special focus on the NAFLD pathogenesis. We will try to answer the question: can we rely on them? |
| first_indexed | 2024-03-11T01:52:32Z |
| format | Article |
| id | doaj.art-d53cacbb8b0c4827b3791fa5c9543c95 |
| institution | Directory Open Access Journal |
| issn | 2673-3943 |
| language | English |
| last_indexed | 2024-03-11T01:52:32Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Transplantology |
| spelling | doaj.art-d53cacbb8b0c4827b3791fa5c9543c952023-11-18T12:55:58ZengMDPI AGTransplantology2673-39432023-05-0142718410.3390/transplantology4020008From NAFLD to Chronic Liver Diseases. Assessment of Liver Fibrosis through Non-Invasive Methods before Liver Transplantation: Can We Rely on Them?Pasquale Auricchio0Michele Finotti1DISCOG, University of Padua, 35182 Padua, ItalyAnnette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX 75204, USAChronic liver injury and subsequent liver fibrosis are usually a slow process without any specific or no clinical signs, resulting in pathological conditions with a poor chance of improvement through medical and surgical treatment, which if not promptly recognized, often lead to a liver transplant as the only therapeutic option. On the other hand, screening and follow-up are hard to establish in large populations using regularly invasive methods such as biopsies and other expensive diagnostic tools due to cost and a lack of adequate specificity and sensibility. In the last few years, a large variety of serological and radiological tests have been proposed to assess liver fibrosis. In this review, we will consider the most commonly used scores to evaluate liver fibrosis, with a special focus on the NAFLD pathogenesis. We will try to answer the question: can we rely on them?https://www.mdpi.com/2673-3943/4/2/8liver fibrosisNAFLDcirrhosisnon-invasive methodsliver transplantation |
| spellingShingle | Pasquale Auricchio Michele Finotti From NAFLD to Chronic Liver Diseases. Assessment of Liver Fibrosis through Non-Invasive Methods before Liver Transplantation: Can We Rely on Them? Transplantology liver fibrosis NAFLD cirrhosis non-invasive methods liver transplantation |
| title | From NAFLD to Chronic Liver Diseases. Assessment of Liver Fibrosis through Non-Invasive Methods before Liver Transplantation: Can We Rely on Them? |
| title_full | From NAFLD to Chronic Liver Diseases. Assessment of Liver Fibrosis through Non-Invasive Methods before Liver Transplantation: Can We Rely on Them? |
| title_fullStr | From NAFLD to Chronic Liver Diseases. Assessment of Liver Fibrosis through Non-Invasive Methods before Liver Transplantation: Can We Rely on Them? |
| title_full_unstemmed | From NAFLD to Chronic Liver Diseases. Assessment of Liver Fibrosis through Non-Invasive Methods before Liver Transplantation: Can We Rely on Them? |
| title_short | From NAFLD to Chronic Liver Diseases. Assessment of Liver Fibrosis through Non-Invasive Methods before Liver Transplantation: Can We Rely on Them? |
| title_sort | from nafld to chronic liver diseases assessment of liver fibrosis through non invasive methods before liver transplantation can we rely on them |
| topic | liver fibrosis NAFLD cirrhosis non-invasive methods liver transplantation |
| url | https://www.mdpi.com/2673-3943/4/2/8 |
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