High plasma concentrations of asymmetric dimethylarginine inhibit ischemic cardioprotection in hypercholesterolemic rats

High plasma concentrations of asymmetric dimethylarginine inhibit ischemic cardioprotection in hypercholesterolemic rats

A low concentration of nitric oxide associated with a high concentration of asymmetric dimethylarginine (ADMA) can explain the lack of ischemic cardioprotection observed in the presence of hypercholesterolemia. The objective of the present study was to evaluate the effect of hypercholesterolemia on...

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Bibliographic Details
Main Authors:	M.B.P. Landim, P.M.M. Dourado, A. Casella-Filho, A.C.P. Chagas, P.L. da-Luz
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2013-10-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Hypercholesterolemia Cardiotonics Nitric oxide Risk factors Asymmetric dimethylarginine
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000500454

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