Acetylcholinesterase Inhibition Properties and Docking Studies of Compounds Based on 6-Hydrazinyl-1,3,4-Trimethyl-1H-Pyrazolo[3,4-b]Pyridine

Acetylcholinesterase Inhibition Properties and Docking Studies of Compounds Based on 6-Hydrazinyl-1,3,4-Trimethyl-1H-Pyrazolo[3,4-b]Pyridine

New compounds based on 6-hydrazinyl-1,3,4-trimethyl-1H-pyrazolo[3,4-b]pyridine (3a and 3b) were synthesized and characterized by FTIR and 1H/13C NMR spectroscopic methods and their in vitro acetylcholinesterase (AChE) inhibition studies were evaluated. Compound 3b (IC50 value 104.4 µM) exhibited str...

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Bibliographic Details
Main Author:	Seyit Ali GÜNGÖR
Format:	Article
Language:	English
Published:	Turkish Chemical Society 2023-02-01
Series:	Journal of the Turkish Chemical Society, Section A: Chemistry
Subjects:	synthesis ache inhibition docking
Online Access:	https://dergipark.org.tr/en/pub/jotcsa/issue/73332/1117324

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