Clinical features of hemichoreahemiballism: A stroke-related movement disorder

We examined pathogenesis and clinical features of three hemichorea-hemiballism (HCHB) cases. We studied their age, magnetic resonance imaging results, vascular risk factors, management, and outcomes. One man and two women (aged 74-86 years) demonstrated acute onset of HCHB, lasting for at least seve...

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Bibliographic Details
Main Authors: Nobuko Shiraiwa, Sachiko Hoshino, Go Saito, Akira Tamaoka, Norio Ohkoshi
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Neurology International
Subjects:
Online Access:https://pagepress.org/journals/index.php/ni/article/view/8328
Description
Summary:We examined pathogenesis and clinical features of three hemichorea-hemiballism (HCHB) cases. We studied their age, magnetic resonance imaging results, vascular risk factors, management, and outcomes. One man and two women (aged 74-86 years) demonstrated acute onset of HCHB, lasting for at least several months. Patients had one or more vascular risk factors, including hypertension and diabetes. All patients presented subacute or old infarction in the basal ganglia with contralateral symptoms. We administered clonazepam (0.5-1 mg/day), haloperidol (0.375-0.75 mg/day), or both as necessary and observed symptom-control. Vascular lesions in the basal ganglia were a contributing factor. Symptoms were controlled using pharmacotherapy with gamma-aminobutyric acid-agonist (clonazepam) or anti-dopaminergic (haloperidol) medication.
ISSN:2035-8385
2035-8377