Bioavailability of orally administered rhGM-CSF: a single-dose, randomized, open-label, two-period crossover trial.

Bioavailability of orally administered rhGM-CSF: a single-dose, randomized, open-label, two-period crossover trial.

BACKGROUND: Recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) is usually administered by injection, and its oral administration in a clinical setting has been not yet reported. Here we demonstrate the bioavailability of orally administered rhGM-CSF in healthy volunteers....

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Bibliographic Details
Main Authors: Wenping Zhang, Zhengbing Lv, Zuoming Nie, Guogang Chen, Jian Chen, Qing Sheng, Wei Yu, Yongfeng Jin, Xiangfu Wu, Yaozhou Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2677157?pdf=render

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