Alleviating Effect of Millet Products on Diarrhea Induced by Senna Leaf in Mice
To study the alleviating effect of different millet products on diarrhea caused by senna leaf in mice. Eighty-four KM mice were randomly divided into 7 groups: Normal control group, model group, positive control group, fermented millet group (6.16 g/kg), ferment millet bran group (2.05 g/kg), millet...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
The editorial department of Science and Technology of Food Industry
2023-05-01
|
| Series: | Shipin gongye ke-ji |
| Subjects: | |
| Online Access: | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022080022 |
| _version_ | 1797737808988733440 |
|---|---|
| author | Shujun CHEN Minquan HAO Lizhen ZHANG |
| author_facet | Shujun CHEN Minquan HAO Lizhen ZHANG |
| author_sort | Shujun CHEN |
| collection | DOAJ |
| description | To study the alleviating effect of different millet products on diarrhea caused by senna leaf in mice. Eighty-four KM mice were randomly divided into 7 groups: Normal control group, model group, positive control group, fermented millet group (6.16 g/kg), ferment millet bran group (2.05 g/kg), millet gruel oil group (10.27 g/kg), and millet bran porridge oil group (10.27 g/kg). Senna leaf was used to establish a diarrhea model in mice. After 7 days of modeling, except for the model group, the other groups were treated for 7 days. The diarrhea index, viscera index, serum inflammatory factors, secretory immunoglobulin A (SIgA) levels, and small intestine section observation were used to evaluate the effects of millet products on diarrhea mice. Compared with the model group, the weight of mice in the millet product group increased significantly on the 13th day (P<0.05), the diarrhea index was significantly decreased (P<0.05), the contents of serum inflammatory factors in ferment millet bran group, fermented millet group, and millet porridge oil group were significantly decreased (P<0.05), the content of secreted immunoglobulin A in intestinal mucosa was significantly increased (P<0.05), small intestine tissue section observation integrity was good. Fermented millet bran, fermented millet, and millet porridge oil in millet products could alleviate diarrhea induced by senna leaf in mice, but the therapeutic mechanism and the changes of intestinal flora in them remain to be further explored. |
| first_indexed | 2024-03-12T13:34:47Z |
| format | Article |
| id | doaj.art-d54eb40aeb1d47f5b2a7ad27997a89e1 |
| institution | Directory Open Access Journal |
| issn | 1002-0306 |
| language | zho |
| last_indexed | 2024-03-12T13:34:47Z |
| publishDate | 2023-05-01 |
| publisher | The editorial department of Science and Technology of Food Industry |
| record_format | Article |
| series | Shipin gongye ke-ji |
| spelling | doaj.art-d54eb40aeb1d47f5b2a7ad27997a89e12023-08-24T06:01:38ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062023-05-01441036236810.13386/j.issn1002-0306.20220800222022080022-10Alleviating Effect of Millet Products on Diarrhea Induced by Senna Leaf in MiceShujun CHEN0Minquan HAO1Lizhen ZHANG2College of Life Science, Shanxi University, Taiyuan 030006, ChinaCollege of Life Science, Shanxi University, Taiyuan 030006, ChinaCollege of Life Science, Shanxi University, Taiyuan 030006, ChinaTo study the alleviating effect of different millet products on diarrhea caused by senna leaf in mice. Eighty-four KM mice were randomly divided into 7 groups: Normal control group, model group, positive control group, fermented millet group (6.16 g/kg), ferment millet bran group (2.05 g/kg), millet gruel oil group (10.27 g/kg), and millet bran porridge oil group (10.27 g/kg). Senna leaf was used to establish a diarrhea model in mice. After 7 days of modeling, except for the model group, the other groups were treated for 7 days. The diarrhea index, viscera index, serum inflammatory factors, secretory immunoglobulin A (SIgA) levels, and small intestine section observation were used to evaluate the effects of millet products on diarrhea mice. Compared with the model group, the weight of mice in the millet product group increased significantly on the 13th day (P<0.05), the diarrhea index was significantly decreased (P<0.05), the contents of serum inflammatory factors in ferment millet bran group, fermented millet group, and millet porridge oil group were significantly decreased (P<0.05), the content of secreted immunoglobulin A in intestinal mucosa was significantly increased (P<0.05), small intestine tissue section observation integrity was good. Fermented millet bran, fermented millet, and millet porridge oil in millet products could alleviate diarrhea induced by senna leaf in mice, but the therapeutic mechanism and the changes of intestinal flora in them remain to be further explored.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022080022milletfermentationfermented millet branmillet gruel oilmillet bran porridge oilanti-diarrheainflammatory factorintestinal mucosa |
| spellingShingle | Shujun CHEN Minquan HAO Lizhen ZHANG Alleviating Effect of Millet Products on Diarrhea Induced by Senna Leaf in Mice Shipin gongye ke-ji millet fermentation fermented millet bran millet gruel oil millet bran porridge oil anti-diarrhea inflammatory factor intestinal mucosa |
| title | Alleviating Effect of Millet Products on Diarrhea Induced by Senna Leaf in Mice |
| title_full | Alleviating Effect of Millet Products on Diarrhea Induced by Senna Leaf in Mice |
| title_fullStr | Alleviating Effect of Millet Products on Diarrhea Induced by Senna Leaf in Mice |
| title_full_unstemmed | Alleviating Effect of Millet Products on Diarrhea Induced by Senna Leaf in Mice |
| title_short | Alleviating Effect of Millet Products on Diarrhea Induced by Senna Leaf in Mice |
| title_sort | alleviating effect of millet products on diarrhea induced by senna leaf in mice |
| topic | millet fermentation fermented millet bran millet gruel oil millet bran porridge oil anti-diarrhea inflammatory factor intestinal mucosa |
| url | http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2022080022 |
| work_keys_str_mv | AT shujunchen alleviatingeffectofmilletproductsondiarrheainducedbysennaleafinmice AT minquanhao alleviatingeffectofmilletproductsondiarrheainducedbysennaleafinmice AT lizhenzhang alleviatingeffectofmilletproductsondiarrheainducedbysennaleafinmice |