Cell-type-specific molecular characterization of cells from circulation and kidney in IgA nephropathy with nephrotic syndrome

Cell-type-specific molecular characterization of cells from circulation and kidney in IgA nephropathy with nephrotic syndrome

Nephrotic syndrome (NS) is a relatively rare and serious presentation of IgA nephropathy (IgAN) (NS-IgAN). Previous research has suggested that the pathogenesis of NS-IgAN may involve circulating immune imbalance and kidney injury; however, this has yet to be fully elucidated. To investigate the cel...

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Bibliographic Details
Main Authors: Qilin Chen, Huimin Jiang, Rong Ding, Jinjie Zhong, Longfei Li, Junli Wan, Xiaoqian Feng, Liping Peng, Xia Yang, Han Chen, Anshuo Wang, Jia Jiao, Qin Yang, Xuelan Chen, Xiaoqin Li, Lin Shi, Gaofu Zhang, Mo Wang, Haiping Yang, Qiu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
IgA nephropathy
nephrotic syndrome
single-cell RNA sequencing
peripheral blood mononuclear cells
podocyte
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1231937/full

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