Ultrasound features of pregnancy‐associated breast cancer: A retrospective observational analysis
Abstract Pregnancy‐associated breast cancer (PABC) is a poor prognosis in women, and the mortality rate is higher in this subgroup of patients than in non‐PABC. This study aims to assess clinicopathological and ultrasound features of patients with PABC. Of 75 patients with breast cancer, 31 cases we...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.4974 |
| _version_ | 1828052343888805888 |
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| author | Maryam Jafari Fereshteh Abbasvandi Elahe Nazeri Asiie Olfatbakhsh Ahmad Kaviani Rezvan Esmaeili |
| author_facet | Maryam Jafari Fereshteh Abbasvandi Elahe Nazeri Asiie Olfatbakhsh Ahmad Kaviani Rezvan Esmaeili |
| author_sort | Maryam Jafari |
| collection | DOAJ |
| description | Abstract Pregnancy‐associated breast cancer (PABC) is a poor prognosis in women, and the mortality rate is higher in this subgroup of patients than in non‐PABC. This study aims to assess clinicopathological and ultrasound features of patients with PABC. Of 75 patients with breast cancer, 31 cases were in lactating, or pregnancy phase and 44 patients had no recent history of pregnancy/lactation at the time of cancer detection. The available pathological characteristics and ultrasound findings of the PABC and non‐PABC groups were compared. The analysis of ultrasound findings demonstrated that the percentages of antiparallel orientation (p = 0.04) and heterogeneous internal echo pattern (p = 0.002) were higher in the PABC group. The final Breast Imaging Reporting and Data System (BI‐RADS) assessment in the two groups was significantly different (p = 0.008). In this study, most PABCs were BI‐RADS 4c or 5; compared with age‐matched non‐PABC cases. There were significant differences in ER (p = 0.03), receptor groups (p = 0.007), and tumor grade (p = 0.02) in PABC compared to non‐PABC group. To conclude, radiologists should be careful about ultrasound findings of PABC and recommend core needle biopsy in suspected cases. |
| first_indexed | 2024-04-10T19:52:11Z |
| format | Article |
| id | doaj.art-d550cf53f5044c4aba2d05b3ca73db12 |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-04-10T19:52:11Z |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-d550cf53f5044c4aba2d05b3ca73db122023-01-28T05:30:04ZengWileyCancer Medicine2045-76342023-01-011221189119410.1002/cam4.4974Ultrasound features of pregnancy‐associated breast cancer: A retrospective observational analysisMaryam Jafari0Fereshteh Abbasvandi1Elahe Nazeri2Asiie Olfatbakhsh3Ahmad Kaviani4Rezvan Esmaeili5Department of Radiology Ali Asghar Children Hospital, Iran University of Medical Sciences Tehran IranATMP Department, Breast Cancer Research Center Motamed Cancer Institute, ACECR Tehran IranGenetics Department, Breast Cancer Research Center Motamed Cancer Institute, ACECR Tehran IranBreast Diseases Department, Breast Cancer Research Center Motamed Cancer Institute, ACECR Tehran IranDepartment of Surgery Tehran University of Medical Science Tehran IranGenetics Department, Breast Cancer Research Center Motamed Cancer Institute, ACECR Tehran IranAbstract Pregnancy‐associated breast cancer (PABC) is a poor prognosis in women, and the mortality rate is higher in this subgroup of patients than in non‐PABC. This study aims to assess clinicopathological and ultrasound features of patients with PABC. Of 75 patients with breast cancer, 31 cases were in lactating, or pregnancy phase and 44 patients had no recent history of pregnancy/lactation at the time of cancer detection. The available pathological characteristics and ultrasound findings of the PABC and non‐PABC groups were compared. The analysis of ultrasound findings demonstrated that the percentages of antiparallel orientation (p = 0.04) and heterogeneous internal echo pattern (p = 0.002) were higher in the PABC group. The final Breast Imaging Reporting and Data System (BI‐RADS) assessment in the two groups was significantly different (p = 0.008). In this study, most PABCs were BI‐RADS 4c or 5; compared with age‐matched non‐PABC cases. There were significant differences in ER (p = 0.03), receptor groups (p = 0.007), and tumor grade (p = 0.02) in PABC compared to non‐PABC group. To conclude, radiologists should be careful about ultrasound findings of PABC and recommend core needle biopsy in suspected cases.https://doi.org/10.1002/cam4.4974BI‐RADSnon‐PABCpathological characteristicspregnancy‐associated breast cancerultrasound |
| spellingShingle | Maryam Jafari Fereshteh Abbasvandi Elahe Nazeri Asiie Olfatbakhsh Ahmad Kaviani Rezvan Esmaeili Ultrasound features of pregnancy‐associated breast cancer: A retrospective observational analysis Cancer Medicine BI‐RADS non‐PABC pathological characteristics pregnancy‐associated breast cancer ultrasound |
| title | Ultrasound features of pregnancy‐associated breast cancer: A retrospective observational analysis |
| title_full | Ultrasound features of pregnancy‐associated breast cancer: A retrospective observational analysis |
| title_fullStr | Ultrasound features of pregnancy‐associated breast cancer: A retrospective observational analysis |
| title_full_unstemmed | Ultrasound features of pregnancy‐associated breast cancer: A retrospective observational analysis |
| title_short | Ultrasound features of pregnancy‐associated breast cancer: A retrospective observational analysis |
| title_sort | ultrasound features of pregnancy associated breast cancer a retrospective observational analysis |
| topic | BI‐RADS non‐PABC pathological characteristics pregnancy‐associated breast cancer ultrasound |
| url | https://doi.org/10.1002/cam4.4974 |
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