Network pharmacology and experimental verification-based strategy to explore the underlying mechanism of Liu Jun An Wei formula in the treatment of gastrointestinal reactions caused by chemotherapy for colorectal cancer
Background: Liu Jun An Wei formula (LJAW), derived from “Liu Jun Zi Decoction”, is a classical prescription of Tradition Chinese Medicine and has been used for the treatment of gastrointestinal reactions caused by chemotherapy for colorectal cancer (CRC) for many years. Its molecular mechanism remai...
Main Authors: | Gaobiao Li, Liying Liu, Yiran Yin, Mengmeng Wang, Lei Wang, Jianwei Dou, Hongwei Wu, Yufei Yang, Bin He |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
|
Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.999115/full |
Similar Items
-
Pharmacokinetic Herb-Drug Interactions of Xiang-Sha-Liu-Jun-Zi-Tang and Paclitaxel in Male Sprague Dawley Rats and Its Influence on Enzyme Kinetics in Human Liver Microsomes
by: Alinafe Magret Kapelemera, et al.
Published: (2022-04-01) -
Compound-target-pathway network analysis and effective mechanisms prediction of Bu-Shen-Jian-Pi formula
by: Xiao-Yan Li, et al.
Published: (2018-01-01) -
Immunomodulatory effects of modified Liu-Wei-Di-Huang-Wan Traditional Chinese medicine on allergic asthmatic mice
by: Jaw-Ji Tsai, et al.
Published: (2023-04-01) -
Arginine Biosynthesis Pathway Found to Play a Key Role in the Neuroprotective Effect of Liu-Wei-Luo-Bi (LWLB) Granules in Diabetic db/db Mice with Peripheral Neuropathy Using an Untargeted Metabolomics Strategy
by: Liu Q, et al.
Published: (2023-12-01) -
The Cao-Xiang-Wei-Kang formula attenuates the progression of experimental colitis by restoring the homeostasis of the microbiome and suppressing inflammation
by: Wei Yu, et al.
Published: (2022-09-01)