GLYCOSAMINOGLYCAN ANALOGUES AS A NOVEL ANTI-INFLAMMATORY STRATEGY

Heparin, a glycosaminoglycan (GAG), has both anti-inflammatory and anti-coagulant properties. The clinical use of heparin against inflammation, however, has been limited by concerns about increased bleeding. While the anticoagulant activity of heparin is well understood, its anti-inflammatory proper...

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Bibliographic Details
Main Author: Amanda E.I. Proudfoot
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00293/full