Maintenance of genome integrity by the late-acting cytoplasmic iron-sulfur assembly (CIA) complex

Maintenance of genome integrity by the late-acting cytoplasmic iron-sulfur assembly (CIA) complex

Iron-sulfur (Fe-S) clusters are unique, redox-active co-factors ubiquitous throughout cellular metabolism. Fe-S cluster synthesis, trafficking, and coordination result from highly coordinated, evolutionarily conserved biosynthetic processes. The initial Fe-S cluster synthesis occurs within the mitoc...

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Bibliographic Details
Main Authors: M. S. Petronek, B. G. Allen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Genetics
Subjects:
iron metabolism
Fe-S biogenesis
genomic integrity
DNA metabolism
CIA complex
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1152398/full

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