Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma
Abstract Neurothekeoma is an uncommon, benign neoplasm presenting in young adults, primarily on the head and neck. It was initially related to nerve sheath myxoma but with the advent of immunohistochemistry, new insights into its cellular differentiation and origin have emerged, unlinking Neurotheke...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2015-06-01
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| Series: | Anais Brasileiros de Dermatologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700156&tlng=en |
| _version_ | 1798015401782673408 |
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| author | Cristián Navarrete-Dechent Maximiliano Curi-Tuma Celeste Marín Sergio González Mauricio Sandoval-Osses |
| author_facet | Cristián Navarrete-Dechent Maximiliano Curi-Tuma Celeste Marín Sergio González Mauricio Sandoval-Osses |
| author_sort | Cristián Navarrete-Dechent |
| collection | DOAJ |
| description | Abstract Neurothekeoma is an uncommon, benign neoplasm presenting in young adults, primarily on the head and neck. It was initially related to nerve sheath myxoma but with the advent of immunohistochemistry, new insights into its cellular differentiation and origin have emerged, unlinking Neurothekeoma and nerve sheath myxoma. Herein we describe a 19-year-old male who had had a frontal, fl esh-colored, asymptomatic papule for 2 years. Histology showed a dermal fusocellular-spindle cell tumor, including an eosinophilic cytoplasm with mild cellular pleomorphism and moderately dense fi brous stroma. IHQ was positive for CD10 and negative for S100 and Claudin-1. These fi ndings were compatible with cellular Neurothekeoma. The lesion was completely extirpated and at the 6-month follow-up, the patient was asymptomatic and had experienced no recurrences. |
| first_indexed | 2024-04-11T15:32:49Z |
| format | Article |
| id | doaj.art-d55809c98e2249379cefc88d6d0d6429 |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-04-11T15:32:49Z |
| publishDate | 2015-06-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-d55809c98e2249379cefc88d6d0d64292022-12-22T04:16:05ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962015-06-01903 suppl 115615910.1590/abd1806-4841.20153402Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxomaCristián Navarrete-DechentMaximiliano Curi-TumaCeleste MarínSergio GonzálezMauricio Sandoval-OssesAbstract Neurothekeoma is an uncommon, benign neoplasm presenting in young adults, primarily on the head and neck. It was initially related to nerve sheath myxoma but with the advent of immunohistochemistry, new insights into its cellular differentiation and origin have emerged, unlinking Neurothekeoma and nerve sheath myxoma. Herein we describe a 19-year-old male who had had a frontal, fl esh-colored, asymptomatic papule for 2 years. Histology showed a dermal fusocellular-spindle cell tumor, including an eosinophilic cytoplasm with mild cellular pleomorphism and moderately dense fi brous stroma. IHQ was positive for CD10 and negative for S100 and Claudin-1. These fi ndings were compatible with cellular Neurothekeoma. The lesion was completely extirpated and at the 6-month follow-up, the patient was asymptomatic and had experienced no recurrences.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700156&tlng=enMyxomaNeoplasms, adnexal and skin appendageNeurothekeoma |
| spellingShingle | Cristián Navarrete-Dechent Maximiliano Curi-Tuma Celeste Marín Sergio González Mauricio Sandoval-Osses Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma Anais Brasileiros de Dermatologia Myxoma Neoplasms, adnexal and skin appendage Neurothekeoma |
| title | Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma |
| title_full | Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma |
| title_fullStr | Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma |
| title_full_unstemmed | Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma |
| title_short | Cellular neurothekeoma: case report and its (un) relation with nerve sheath myxoma |
| title_sort | cellular neurothekeoma case report and its un relation with nerve sheath myxoma |
| topic | Myxoma Neoplasms, adnexal and skin appendage Neurothekeoma |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700156&tlng=en |
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