Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets
A system for measuring small oil droplets in an oil-in-water (O/W) emulsion was developed using multiphoton ionization time-of-flight mass spectrometry. In the present study, a capillary column with an inner diameter of 15 µm was used for sample introduction. Moreover, a compact microscopic system w...
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MDPI AG
2018-03-01
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Online Access: | http://www.mdpi.com/2076-3417/8/3/413 |
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author | Chiaki Fujita Yoshiki Sugimura Tomohiro Uchimura |
author_facet | Chiaki Fujita Yoshiki Sugimura Tomohiro Uchimura |
author_sort | Chiaki Fujita |
collection | DOAJ |
description | A system for measuring small oil droplets in an oil-in-water (O/W) emulsion was developed using multiphoton ionization time-of-flight mass spectrometry. In the present study, a capillary column with an inner diameter of 15 µm was used for sample introduction. Moreover, a compact microscopic system was constructed for observing an emulsion flowing through a capillary column. As a result, the length for sample introduction was shortened, which is preferable for the direct evaluation of an emulsion. Using this system, the minimum diameter of a detectable toluene droplet in an O/W emulsion was decreased to 1.7 µm. The present system could be used to evaluate the local microenvironment and stability of an emulsion. |
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format | Article |
id | doaj.art-d56011643add4b738d542c1d68f2afc8 |
institution | Directory Open Access Journal |
issn | 2076-3417 |
language | English |
last_indexed | 2024-04-14T06:14:26Z |
publishDate | 2018-03-01 |
publisher | MDPI AG |
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series | Applied Sciences |
spelling | doaj.art-d56011643add4b738d542c1d68f2afc82022-12-22T02:08:16ZengMDPI AGApplied Sciences2076-34172018-03-018341310.3390/app8030413app8030413Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion DropletsChiaki Fujita0Yoshiki Sugimura1Tomohiro Uchimura2Department of Materials Science and Engineering, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, JapanDepartment of Materials Science and Engineering, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, JapanDepartment of Materials Science and Engineering, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, JapanA system for measuring small oil droplets in an oil-in-water (O/W) emulsion was developed using multiphoton ionization time-of-flight mass spectrometry. In the present study, a capillary column with an inner diameter of 15 µm was used for sample introduction. Moreover, a compact microscopic system was constructed for observing an emulsion flowing through a capillary column. As a result, the length for sample introduction was shortened, which is preferable for the direct evaluation of an emulsion. Using this system, the minimum diameter of a detectable toluene droplet in an O/W emulsion was decreased to 1.7 µm. The present system could be used to evaluate the local microenvironment and stability of an emulsion.http://www.mdpi.com/2076-3417/8/3/413MPI-TOFMSO/W emulsionemulsion droplet |
spellingShingle | Chiaki Fujita Yoshiki Sugimura Tomohiro Uchimura Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets Applied Sciences MPI-TOFMS O/W emulsion emulsion droplet |
title | Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets |
title_full | Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets |
title_fullStr | Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets |
title_full_unstemmed | Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets |
title_short | Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets |
title_sort | development of multiphoton ionization time of flight mass spectrometry for the detection of small emulsion droplets |
topic | MPI-TOFMS O/W emulsion emulsion droplet |
url | http://www.mdpi.com/2076-3417/8/3/413 |
work_keys_str_mv | AT chiakifujita developmentofmultiphotonionizationtimeofflightmassspectrometryforthedetectionofsmallemulsiondroplets AT yoshikisugimura developmentofmultiphotonionizationtimeofflightmassspectrometryforthedetectionofsmallemulsiondroplets AT tomohirouchimura developmentofmultiphotonionizationtimeofflightmassspectrometryforthedetectionofsmallemulsiondroplets |