Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets

A system for measuring small oil droplets in an oil-in-water (O/W) emulsion was developed using multiphoton ionization time-of-flight mass spectrometry. In the present study, a capillary column with an inner diameter of 15 µm was used for sample introduction. Moreover, a compact microscopic system w...

Full description

Bibliographic Details
Main Authors: Chiaki Fujita, Yoshiki Sugimura, Tomohiro Uchimura
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Applied Sciences
Subjects:
Online Access:http://www.mdpi.com/2076-3417/8/3/413
_version_ 1818011912451915776
author Chiaki Fujita
Yoshiki Sugimura
Tomohiro Uchimura
author_facet Chiaki Fujita
Yoshiki Sugimura
Tomohiro Uchimura
author_sort Chiaki Fujita
collection DOAJ
description A system for measuring small oil droplets in an oil-in-water (O/W) emulsion was developed using multiphoton ionization time-of-flight mass spectrometry. In the present study, a capillary column with an inner diameter of 15 µm was used for sample introduction. Moreover, a compact microscopic system was constructed for observing an emulsion flowing through a capillary column. As a result, the length for sample introduction was shortened, which is preferable for the direct evaluation of an emulsion. Using this system, the minimum diameter of a detectable toluene droplet in an O/W emulsion was decreased to 1.7 µm. The present system could be used to evaluate the local microenvironment and stability of an emulsion.
first_indexed 2024-04-14T06:14:26Z
format Article
id doaj.art-d56011643add4b738d542c1d68f2afc8
institution Directory Open Access Journal
issn 2076-3417
language English
last_indexed 2024-04-14T06:14:26Z
publishDate 2018-03-01
publisher MDPI AG
record_format Article
series Applied Sciences
spelling doaj.art-d56011643add4b738d542c1d68f2afc82022-12-22T02:08:16ZengMDPI AGApplied Sciences2076-34172018-03-018341310.3390/app8030413app8030413Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion DropletsChiaki Fujita0Yoshiki Sugimura1Tomohiro Uchimura2Department of Materials Science and Engineering, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, JapanDepartment of Materials Science and Engineering, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, JapanDepartment of Materials Science and Engineering, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui 910-8507, JapanA system for measuring small oil droplets in an oil-in-water (O/W) emulsion was developed using multiphoton ionization time-of-flight mass spectrometry. In the present study, a capillary column with an inner diameter of 15 µm was used for sample introduction. Moreover, a compact microscopic system was constructed for observing an emulsion flowing through a capillary column. As a result, the length for sample introduction was shortened, which is preferable for the direct evaluation of an emulsion. Using this system, the minimum diameter of a detectable toluene droplet in an O/W emulsion was decreased to 1.7 µm. The present system could be used to evaluate the local microenvironment and stability of an emulsion.http://www.mdpi.com/2076-3417/8/3/413MPI-TOFMSO/W emulsionemulsion droplet
spellingShingle Chiaki Fujita
Yoshiki Sugimura
Tomohiro Uchimura
Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets
Applied Sciences
MPI-TOFMS
O/W emulsion
emulsion droplet
title Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets
title_full Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets
title_fullStr Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets
title_full_unstemmed Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets
title_short Development of Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Small Emulsion Droplets
title_sort development of multiphoton ionization time of flight mass spectrometry for the detection of small emulsion droplets
topic MPI-TOFMS
O/W emulsion
emulsion droplet
url http://www.mdpi.com/2076-3417/8/3/413
work_keys_str_mv AT chiakifujita developmentofmultiphotonionizationtimeofflightmassspectrometryforthedetectionofsmallemulsiondroplets
AT yoshikisugimura developmentofmultiphotonionizationtimeofflightmassspectrometryforthedetectionofsmallemulsiondroplets
AT tomohirouchimura developmentofmultiphotonionizationtimeofflightmassspectrometryforthedetectionofsmallemulsiondroplets