The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis
In recent years, the gut microbiota has been considered as a full-fledged actor of the gut–brain axis, making it possible to take a new step in understanding the pathophysiology of both neurological and psychiatric diseases. However, most of the studies have been devoted to gut bacterial microbiota,...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-03-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-2607/6/1/22 |
| _version_ | 1818558299969159168 |
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| author | Raphaël Enaud Louise-Eva Vandenborght Noémie Coron Thomas Bazin Renaud Prevel Thierry Schaeverbeke Patrick Berger Michael Fayon Thierry Lamireau Laurence Delhaes |
| author_facet | Raphaël Enaud Louise-Eva Vandenborght Noémie Coron Thomas Bazin Renaud Prevel Thierry Schaeverbeke Patrick Berger Michael Fayon Thierry Lamireau Laurence Delhaes |
| author_sort | Raphaël Enaud |
| collection | DOAJ |
| description | In recent years, the gut microbiota has been considered as a full-fledged actor of the gut–brain axis, making it possible to take a new step in understanding the pathophysiology of both neurological and psychiatric diseases. However, most of the studies have been devoted to gut bacterial microbiota, forgetting the non-negligible fungal flora. In this review, we expose how the role of the fungal component in the microbiota-gut-brain axis is legitimate, through its interactions with both the host, especially with the immune system, and the gut bacteria. We also discuss published data that already attest to a role of the mycobiome in the microbiota-gut-brain axis, and the impact of fungi on clinical and therapeutic research. |
| first_indexed | 2024-12-14T00:10:49Z |
| format | Article |
| id | doaj.art-d561969e1e474b6f967d9db3e833732a |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-12-14T00:10:49Z |
| publishDate | 2018-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-d561969e1e474b6f967d9db3e833732a2022-12-21T23:25:46ZengMDPI AGMicroorganisms2076-26072018-03-01612210.3390/microorganisms6010022microorganisms6010022The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain AxisRaphaël Enaud0Louise-Eva Vandenborght1Noémie Coron2Thomas Bazin3Renaud Prevel4Thierry Schaeverbeke5Patrick Berger6Michael Fayon7Thierry Lamireau8Laurence Delhaes9Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceCentre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceCentre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceCentre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceCentre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceCentre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceCentre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceCentre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceCentre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceCentre de Recherche Cardio-Thoracique de Bordeaux, U1045, FHU ACRONIM, University Bordeaux,33000 Bordeaux, FranceIn recent years, the gut microbiota has been considered as a full-fledged actor of the gut–brain axis, making it possible to take a new step in understanding the pathophysiology of both neurological and psychiatric diseases. However, most of the studies have been devoted to gut bacterial microbiota, forgetting the non-negligible fungal flora. In this review, we expose how the role of the fungal component in the microbiota-gut-brain axis is legitimate, through its interactions with both the host, especially with the immune system, and the gut bacteria. We also discuss published data that already attest to a role of the mycobiome in the microbiota-gut-brain axis, and the impact of fungi on clinical and therapeutic research.http://www.mdpi.com/2076-2607/6/1/22brain–gut axismycobiomemicrobiomedysbiosisneurological disorderspsychiatric disordersfungus |
| spellingShingle | Raphaël Enaud Louise-Eva Vandenborght Noémie Coron Thomas Bazin Renaud Prevel Thierry Schaeverbeke Patrick Berger Michael Fayon Thierry Lamireau Laurence Delhaes The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis Microorganisms brain–gut axis mycobiome microbiome dysbiosis neurological disorders psychiatric disorders fungus |
| title | The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis |
| title_full | The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis |
| title_fullStr | The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis |
| title_full_unstemmed | The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis |
| title_short | The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis |
| title_sort | mycobiome a neglected component in the microbiota gut brain axis |
| topic | brain–gut axis mycobiome microbiome dysbiosis neurological disorders psychiatric disorders fungus |
| url | http://www.mdpi.com/2076-2607/6/1/22 |
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