The Role of Vitamin D on the Wound Healing Process: A Case Series
Fitri Dona Siregar,1 Wahyu Hidayat2 1Speciality Program of Oral Medicine, Faculty of Dentistry Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Department of Oral Medicine, Faculty of Dentistry Universitas Padjadjaran, Bandung, West Java, IndonesiaCorrespondence: Fitri Dona Siregar, Faculty...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2023-04-01
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| Series: | International Medical Case Reports Journal |
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| Online Access: | https://www.dovepress.com/the-role-of-vitamin-d-on-the-wound-healing-process-a-case-series-peer-reviewed-fulltext-article-IMCRJ |
| _version_ | 1797854230798663680 |
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| author | Siregar FD Hidayat W |
| author_facet | Siregar FD Hidayat W |
| author_sort | Siregar FD |
| collection | DOAJ |
| description | Fitri Dona Siregar,1 Wahyu Hidayat2 1Speciality Program of Oral Medicine, Faculty of Dentistry Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Department of Oral Medicine, Faculty of Dentistry Universitas Padjadjaran, Bandung, West Java, IndonesiaCorrespondence: Fitri Dona Siregar, Faculty of Dentistry Universitas Padjadjaran, Jl. Sekeloa Selatan I No. 1, Bandung, West Java, 40132, Indonesia, Email fitri20012@mail.unpad.ac.idIntroduction: Vitamin D is an essential steroid hormone that consists of two forms, namely vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol), which can be obtained from exposure to sunlight, synthesis of vitamin D in the skin, food and dietary supplements. Prevalence of vitamin D deficiency in several countries including Indonesia is still high, while the role of vitamin D is very important including accelerating the wound healing process, increasing the immune system, anti-inflammatory, and anti-bacterial.Purpose: This case report aims to find out the role of vitamin D in the wound-healing process in the oral mucosa.Case Reports: Two men went to the Oral Disease Clinic with complaints of canker sores on the oral mucosa for more than a month accompanied by pain. Intra-oral condition in the first patient showed multiple ulcers with yellowish white base surrounded by erythematous areas, well-defined, irregular with a size of 1.5 × 1 cm and 1 × 0.5 cm on the right and left buccal mucosa, while intra-oral in the second patient, a single ulcer with a base was found yellowish colour surrounded by erythematous area, oval measuring 3x1 cm, clearly demarcated with induration.Results: Laboratory examination of vitamin D in both patients showed decreased levels of vitamin D with values of 28.7 and 9.8 ng/mL.Conclusion: Vitamin D supplementation has shown effectiveness in wound-healing processes in the oral mucosa.Keywords: vitamin D, role, immune system, wound healing, mouth ulceration |
| first_indexed | 2024-04-09T20:03:43Z |
| format | Article |
| id | doaj.art-d5620592282a485bb9aef565249d95e2 |
| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-04-09T20:03:43Z |
| publishDate | 2023-04-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-d5620592282a485bb9aef565249d95e22023-04-02T19:44:15ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2023-04-01Volume 1622723282710The Role of Vitamin D on the Wound Healing Process: A Case SeriesSiregar FDHidayat WFitri Dona Siregar,1 Wahyu Hidayat2 1Speciality Program of Oral Medicine, Faculty of Dentistry Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Department of Oral Medicine, Faculty of Dentistry Universitas Padjadjaran, Bandung, West Java, IndonesiaCorrespondence: Fitri Dona Siregar, Faculty of Dentistry Universitas Padjadjaran, Jl. Sekeloa Selatan I No. 1, Bandung, West Java, 40132, Indonesia, Email fitri20012@mail.unpad.ac.idIntroduction: Vitamin D is an essential steroid hormone that consists of two forms, namely vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol), which can be obtained from exposure to sunlight, synthesis of vitamin D in the skin, food and dietary supplements. Prevalence of vitamin D deficiency in several countries including Indonesia is still high, while the role of vitamin D is very important including accelerating the wound healing process, increasing the immune system, anti-inflammatory, and anti-bacterial.Purpose: This case report aims to find out the role of vitamin D in the wound-healing process in the oral mucosa.Case Reports: Two men went to the Oral Disease Clinic with complaints of canker sores on the oral mucosa for more than a month accompanied by pain. Intra-oral condition in the first patient showed multiple ulcers with yellowish white base surrounded by erythematous areas, well-defined, irregular with a size of 1.5 × 1 cm and 1 × 0.5 cm on the right and left buccal mucosa, while intra-oral in the second patient, a single ulcer with a base was found yellowish colour surrounded by erythematous area, oval measuring 3x1 cm, clearly demarcated with induration.Results: Laboratory examination of vitamin D in both patients showed decreased levels of vitamin D with values of 28.7 and 9.8 ng/mL.Conclusion: Vitamin D supplementation has shown effectiveness in wound-healing processes in the oral mucosa.Keywords: vitamin D, role, immune system, wound healing, mouth ulcerationhttps://www.dovepress.com/the-role-of-vitamin-d-on-the-wound-healing-process-a-case-series-peer-reviewed-fulltext-article-IMCRJvitamin droleimmune systemwound healingmouth ulceration |
| spellingShingle | Siregar FD Hidayat W The Role of Vitamin D on the Wound Healing Process: A Case Series International Medical Case Reports Journal vitamin d role immune system wound healing mouth ulceration |
| title | The Role of Vitamin D on the Wound Healing Process: A Case Series |
| title_full | The Role of Vitamin D on the Wound Healing Process: A Case Series |
| title_fullStr | The Role of Vitamin D on the Wound Healing Process: A Case Series |
| title_full_unstemmed | The Role of Vitamin D on the Wound Healing Process: A Case Series |
| title_short | The Role of Vitamin D on the Wound Healing Process: A Case Series |
| title_sort | role of vitamin d on the wound healing process a case series |
| topic | vitamin d role immune system wound healing mouth ulceration |
| url | https://www.dovepress.com/the-role-of-vitamin-d-on-the-wound-healing-process-a-case-series-peer-reviewed-fulltext-article-IMCRJ |
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