Synthesis of DPIE [2-(1,2-Diphenyl-1<i>H</i>-indol-3-yl)ethanamine] Derivatives and Their Regulatory Effects on Pro-Inflammatory Cytokine Production in IL-1β-Stimulated Primary Human Oral Cells
Interleukin-1 beta (IL-1β) has diverse physiological functions and plays important roles in health and disease. In this report, we focus on its function in the production of pro-inflammatory cytokines, including IL-6 and IL-8, which are implicated in several autoimmune diseases and host defense agai...
Main Authors: | Jeongah Lim, Jihyoun Seong, Seunggon Jung, Tae-Hoon Lee, Eunae Kim, Sunwoo Lee |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-01-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/27/3/899 |
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