Nutritional supplementation in patients with chronic obstructive pulmonary disease
Malnutrition in patients with chronic obstructive pulmonary disease (COPD) is associated with cachexia, sarcopenia, and weight loss, and may result in poorer pulmonary function, decreased exercise capacity, and increased risk of exacerbations. Providing nutritional supplementation is an important th...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-08-01
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| Series: | Journal of the Formosan Medical Association |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664615003460 |
| _version_ | 1819050104125915136 |
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| author | Meng-Jer Hsieh Tsung-Ming Yang Ying-Huang Tsai |
| author_facet | Meng-Jer Hsieh Tsung-Ming Yang Ying-Huang Tsai |
| author_sort | Meng-Jer Hsieh |
| collection | DOAJ |
| description | Malnutrition in patients with chronic obstructive pulmonary disease (COPD) is associated with cachexia, sarcopenia, and weight loss, and may result in poorer pulmonary function, decreased exercise capacity, and increased risk of exacerbations. Providing nutritional supplementation is an important therapeutic intervention, particularly for severely ill COPD patients with malnutrition. Higher calorie intake through nutritional supplementation significantly increases body weight and muscle strength, and improves quality of life in malnourished COPD patients. Difficulties may be experienced by these COPD patients, who are struggling to breathe and eliminate CO2 from the lungs, resulting in dyspnea, hypercapnia, hypoxia, and respiratory acidosis, which exacerbates muscle loss through oxidative stress and inflammatory responses. To overcome these problems, nutritional supplements should aim to reduce metabolic CO2 production, lower respiratory quotient, and improve lung function. Several studies have shown that high-fat supplements produce less CO2 and have lower respiratory quotient value than high-carbohydrate supplements. In addition, high-fat supplements may be the most efficient means of providing a low-volume, calorie-dense supplement to COPD patients, and may be most beneficial to patients with prolonged mechanical ventilation where hypercapnia and malnutrition are most pronounced. Further studies are required to investigate the optimal nutritional supplements for COPD patients according to their disease severity. |
| first_indexed | 2024-12-21T11:42:44Z |
| format | Article |
| id | doaj.art-d56866a17f854bfc9fb4757a9d69b2ca |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-21T11:42:44Z |
| publishDate | 2016-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-d56866a17f854bfc9fb4757a9d69b2ca2022-12-21T19:05:16ZengElsevierJournal of the Formosan Medical Association0929-66462016-08-01115859560110.1016/j.jfma.2015.10.008Nutritional supplementation in patients with chronic obstructive pulmonary diseaseMeng-Jer Hsieh0Tsung-Ming Yang1Ying-Huang Tsai2Department of Pulmonary and Critical Care Medicine, Chiayi Chang-Gung Memorial Hospital, Chang-Gung Medical Foundation, Puzi City, TaiwanDepartment of Pulmonary and Critical Care Medicine, Chiayi Chang-Gung Memorial Hospital, Chang-Gung Medical Foundation, Puzi City, TaiwanDepartment of Pulmonary and Critical Care Medicine, Chiayi Chang-Gung Memorial Hospital, Chang-Gung Medical Foundation, Puzi City, TaiwanMalnutrition in patients with chronic obstructive pulmonary disease (COPD) is associated with cachexia, sarcopenia, and weight loss, and may result in poorer pulmonary function, decreased exercise capacity, and increased risk of exacerbations. Providing nutritional supplementation is an important therapeutic intervention, particularly for severely ill COPD patients with malnutrition. Higher calorie intake through nutritional supplementation significantly increases body weight and muscle strength, and improves quality of life in malnourished COPD patients. Difficulties may be experienced by these COPD patients, who are struggling to breathe and eliminate CO2 from the lungs, resulting in dyspnea, hypercapnia, hypoxia, and respiratory acidosis, which exacerbates muscle loss through oxidative stress and inflammatory responses. To overcome these problems, nutritional supplements should aim to reduce metabolic CO2 production, lower respiratory quotient, and improve lung function. Several studies have shown that high-fat supplements produce less CO2 and have lower respiratory quotient value than high-carbohydrate supplements. In addition, high-fat supplements may be the most efficient means of providing a low-volume, calorie-dense supplement to COPD patients, and may be most beneficial to patients with prolonged mechanical ventilation where hypercapnia and malnutrition are most pronounced. Further studies are required to investigate the optimal nutritional supplements for COPD patients according to their disease severity.http://www.sciencedirect.com/science/article/pii/S0929664615003460chronic obstructive pulmonary diseasemalnutritionnutritional supportweight loss |
| spellingShingle | Meng-Jer Hsieh Tsung-Ming Yang Ying-Huang Tsai Nutritional supplementation in patients with chronic obstructive pulmonary disease Journal of the Formosan Medical Association chronic obstructive pulmonary disease malnutrition nutritional support weight loss |
| title | Nutritional supplementation in patients with chronic obstructive pulmonary disease |
| title_full | Nutritional supplementation in patients with chronic obstructive pulmonary disease |
| title_fullStr | Nutritional supplementation in patients with chronic obstructive pulmonary disease |
| title_full_unstemmed | Nutritional supplementation in patients with chronic obstructive pulmonary disease |
| title_short | Nutritional supplementation in patients with chronic obstructive pulmonary disease |
| title_sort | nutritional supplementation in patients with chronic obstructive pulmonary disease |
| topic | chronic obstructive pulmonary disease malnutrition nutritional support weight loss |
| url | http://www.sciencedirect.com/science/article/pii/S0929664615003460 |
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