Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS

Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS

The antiviral innate immunity is the first line of host defense against viral infection. Mitochondrial antiviral signaling protein (MAVS, also named Cardif/IPS-1/VISA) is a critical protein in RNA virus-induced antiviral signaling pathways. Our previous research suggested that E3 ubiquitin-protein l...

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Bibliographic Details
Main Authors: Bo Yang, Ge Zhang, Xiao Qin, Yulu Huang, Xiaowen Ren, Jingliang Sun, Shujun Ma, Yanzi Liu, Di Song, Yue Liu, Yuhan Cui, Hui Wang, Jie Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
antiviral innate immune responses
ubiquitination
degradation
signaling pathway
MAVS
RNF90
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.730483/full

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