Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary study
Background/Purpose: To evaluate the therapeutic responsiveness of office-based salivary gland ductal irrigation in patients with chronic sialoadenitis. Methods: Between August 2017 and April 2019, 55 patients comprising the following three disease groups were enrolled: Sjogren’s syndrome: 39 patient...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-01-01
|
| Series: | Journal of the Formosan Medical Association |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664620304642 |
| _version_ | 1818603722150772736 |
|---|---|
| author | Yen-Chun Chen Luong Huu Dang Lung-Che Chen Chi-Ching Chang Deng-Yu Han Chung-Huei Hsu Yi-Fang Ding Chin-Hui Su Shih-Han Hung |
| author_facet | Yen-Chun Chen Luong Huu Dang Lung-Che Chen Chi-Ching Chang Deng-Yu Han Chung-Huei Hsu Yi-Fang Ding Chin-Hui Su Shih-Han Hung |
| author_sort | Yen-Chun Chen |
| collection | DOAJ |
| description | Background/Purpose: To evaluate the therapeutic responsiveness of office-based salivary gland ductal irrigation in patients with chronic sialoadenitis. Methods: Between August 2017 and April 2019, 55 patients comprising the following three disease groups were enrolled: Sjogren’s syndrome: 39 patients; postradiotherapy sialoadenitis: ten patients; and post-RAI sialoadenitis: six patients. Quantitative salivary scintigraphy was recorded, and a formulated questionnaire including the Summated Xerostomia Inventory was utilized to assess acute/chronic symptoms. All patients received at least three serial salivary gland ductal irrigations with a one-month interval in our outpatient department. Results: The general response rates for each disease groups are as follows: Sjogren’s syndrome: 61.5% (24/39); postradiotherapy: 60% (6/10); and post-RAI: 83.3% (5/6). Among the patients with Sjogren’s syndrome, the parotid scintigraphic Tmin showed a significant positive correlation with the responsiveness of salivary irrigation (P = 0.046), whereas the treatment tended to be irresponsive in patients who previously took medicine for their related discomfort (P = 0.009). In the postradiotherapy and post-RAI groups, no significant factors were found to be associated with the responsiveness of irrigation. Conclusion: Simple salivary ductal irrigation without complex equipment can be performed as an outpatient procedure to alleviate glandular swelling or xerostomia in patients with Sjogren's syndrome, postradiotherapy sialoadenitis or post-RAI sialoadenitis, and it can be considered an alternative management approach for patients refractory to conventional strategies. |
| first_indexed | 2024-12-16T13:27:41Z |
| format | Article |
| id | doaj.art-d56b0cdcf5ad4788a96f0dbdb6f87d0f |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-12-16T13:27:41Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-d56b0cdcf5ad4788a96f0dbdb6f87d0f2022-12-21T22:30:11ZengElsevierJournal of the Formosan Medical Association0929-66462021-01-011201318326Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary studyYen-Chun Chen0Luong Huu Dang1Lung-Che Chen2Chi-Ching Chang3Deng-Yu Han4Chung-Huei Hsu5Yi-Fang Ding6Chin-Hui Su7Shih-Han Hung8Department of Otolaryngology, Taipei Medical University Hospital, Taipei, TaiwanInternational Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; University of Medicine and Pharmacy at Ho Chi Minh City, VietnamDepartment of Otolaryngology, Taipei Medical University Hospital, Taipei, TaiwanDivision of Rheumatology, Immunology and Allergy, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, TaiwanDepartment of Nuclear Medicine, Taipei Medical University Hospital, Taipei, TaiwanDepartment of Nuclear Medicine, Taipei Medical University Hospital, Taipei, Taiwan; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, TaiwanDepartment of Otolaryngology, Wan-Fang Hospital, Taipei Medical University, Taipei, TaiwanDepartment of Otolaryngology, Mackay Memorial Hospital, Taipei, TaiwanInternational Master/Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Otolaryngology, Wan-Fang Hospital, Taipei Medical University, Taipei, Taiwan; Department of Otolaryngology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Corresponding author. Department of Otolaryngology, Wan-Fang Hospital, Taipei Medical University, Taipei, Taiwan.Background/Purpose: To evaluate the therapeutic responsiveness of office-based salivary gland ductal irrigation in patients with chronic sialoadenitis. Methods: Between August 2017 and April 2019, 55 patients comprising the following three disease groups were enrolled: Sjogren’s syndrome: 39 patients; postradiotherapy sialoadenitis: ten patients; and post-RAI sialoadenitis: six patients. Quantitative salivary scintigraphy was recorded, and a formulated questionnaire including the Summated Xerostomia Inventory was utilized to assess acute/chronic symptoms. All patients received at least three serial salivary gland ductal irrigations with a one-month interval in our outpatient department. Results: The general response rates for each disease groups are as follows: Sjogren’s syndrome: 61.5% (24/39); postradiotherapy: 60% (6/10); and post-RAI: 83.3% (5/6). Among the patients with Sjogren’s syndrome, the parotid scintigraphic Tmin showed a significant positive correlation with the responsiveness of salivary irrigation (P = 0.046), whereas the treatment tended to be irresponsive in patients who previously took medicine for their related discomfort (P = 0.009). In the postradiotherapy and post-RAI groups, no significant factors were found to be associated with the responsiveness of irrigation. Conclusion: Simple salivary ductal irrigation without complex equipment can be performed as an outpatient procedure to alleviate glandular swelling or xerostomia in patients with Sjogren's syndrome, postradiotherapy sialoadenitis or post-RAI sialoadenitis, and it can be considered an alternative management approach for patients refractory to conventional strategies.http://www.sciencedirect.com/science/article/pii/S0929664620304642Salivary ductal irrigationSjogren's syndromePostradiotherapy sialoadenitisPost-RAI sialoadenitisSalivary scintigraphy |
| spellingShingle | Yen-Chun Chen Luong Huu Dang Lung-Che Chen Chi-Ching Chang Deng-Yu Han Chung-Huei Hsu Yi-Fang Ding Chin-Hui Su Shih-Han Hung Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary study Journal of the Formosan Medical Association Salivary ductal irrigation Sjogren's syndrome Postradiotherapy sialoadenitis Post-RAI sialoadenitis Salivary scintigraphy |
| title | Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary study |
| title_full | Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary study |
| title_fullStr | Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary study |
| title_full_unstemmed | Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary study |
| title_short | Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis: A preliminary study |
| title_sort | office based salivary gland ductal irrigation in patients with chronic sialoadenitis a preliminary study |
| topic | Salivary ductal irrigation Sjogren's syndrome Postradiotherapy sialoadenitis Post-RAI sialoadenitis Salivary scintigraphy |
| url | http://www.sciencedirect.com/science/article/pii/S0929664620304642 |
| work_keys_str_mv | AT yenchunchen officebasedsalivaryglandductalirrigationinpatientswithchronicsialoadenitisapreliminarystudy AT luonghuudang officebasedsalivaryglandductalirrigationinpatientswithchronicsialoadenitisapreliminarystudy AT lungchechen officebasedsalivaryglandductalirrigationinpatientswithchronicsialoadenitisapreliminarystudy AT chichingchang officebasedsalivaryglandductalirrigationinpatientswithchronicsialoadenitisapreliminarystudy AT dengyuhan officebasedsalivaryglandductalirrigationinpatientswithchronicsialoadenitisapreliminarystudy AT chunghueihsu officebasedsalivaryglandductalirrigationinpatientswithchronicsialoadenitisapreliminarystudy AT yifangding officebasedsalivaryglandductalirrigationinpatientswithchronicsialoadenitisapreliminarystudy AT chinhuisu officebasedsalivaryglandductalirrigationinpatientswithchronicsialoadenitisapreliminarystudy AT shihhanhung officebasedsalivaryglandductalirrigationinpatientswithchronicsialoadenitisapreliminarystudy |