St. John\'s wort (Hypericum perforatum L.): A Review
Hypericum perforatum L., also known St. John's wort, is a herbaceous perennial belonging to Hypericaceae family that is a native of Western Europe, North Africa, and Asia. The importance of this plant as a phytopharmaceutical, especially for treatment of mild to- moderately severe depression, h...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Institue of Medicinal Plants, ACECR
2005-12-01
|
| Series: | Journal of Medicinal Plants |
| Subjects: | |
| Online Access: | http://jmp.ir/article-1-683-en.html |
| _version_ | 1818725894351486976 |
|---|---|
| author | H Naghdi Badi G Amin M Makkizadeh SA Ziai |
| author_facet | H Naghdi Badi G Amin M Makkizadeh SA Ziai |
| author_sort | H Naghdi Badi |
| collection | DOAJ |
| description | Hypericum perforatum L., also known St. John's wort, is a herbaceous perennial belonging to Hypericaceae family that is a native of Western Europe, North Africa, and Asia. The importance of this plant as a phytopharmaceutical, especially for treatment of mild to- moderately severe depression, has significantly increased in the last few years. The major active constituents are considered to be Hypericin (a naphtodianthrone) and Hyperforin (a prenylated phloroglucinol), although other biologically active constituents eg. Flavoneids and tannins are also present. However, Hypericin is utilized as the key compound in measuring the quality of St.Johns wort and is typically used as the measure of extract potency, although recent studies indicated that hyperforin may be the antidepressive agent in St. John's wort. However, St. John's wort is one of the top- selling herbal products, which has an important place in world market. |
| first_indexed | 2024-12-17T21:49:34Z |
| format | Article |
| id | doaj.art-d56bd69c46204e888bd66a5306285e8b |
| institution | Directory Open Access Journal |
| issn | 2717-204X 2717-2058 |
| language | English |
| last_indexed | 2024-12-17T21:49:34Z |
| publishDate | 2005-12-01 |
| publisher | Institue of Medicinal Plants, ACECR |
| record_format | Article |
| series | Journal of Medicinal Plants |
| spelling | doaj.art-d56bd69c46204e888bd66a5306285e8b2022-12-21T21:31:21ZengInstitue of Medicinal Plants, ACECRJournal of Medicinal Plants2717-204X2717-20582005-12-01416114St. John\'s wort (Hypericum perforatum L.): A ReviewH Naghdi Badi0G Amin1M Makkizadeh2SA Ziai3 1- Institute of Medicinal Plants, ACECR and Tarbiat Modarres University, Tehran, Iran 2- Faculty of Pharmacy, Tehran University of Medical Science (TUMS), Tehran, Iran 3- Institute of Medicinal Plants, ACECR, Tehran, Iran 3- Institute of Medicinal Plants, ACECR, Tehran, Iran Hypericum perforatum L., also known St. John's wort, is a herbaceous perennial belonging to Hypericaceae family that is a native of Western Europe, North Africa, and Asia. The importance of this plant as a phytopharmaceutical, especially for treatment of mild to- moderately severe depression, has significantly increased in the last few years. The major active constituents are considered to be Hypericin (a naphtodianthrone) and Hyperforin (a prenylated phloroglucinol), although other biologically active constituents eg. Flavoneids and tannins are also present. However, Hypericin is utilized as the key compound in measuring the quality of St.Johns wort and is typically used as the measure of extract potency, although recent studies indicated that hyperforin may be the antidepressive agent in St. John's wort. However, St. John's wort is one of the top- selling herbal products, which has an important place in world market.http://jmp.ir/article-1-683-en.htmlst. john’s worthypericinhypericinhyperforindepression |
| spellingShingle | H Naghdi Badi G Amin M Makkizadeh SA Ziai St. John\'s wort (Hypericum perforatum L.): A Review Journal of Medicinal Plants st. john’s wort hypericin hypericin hyperforin depression |
| title | St. John\'s wort (Hypericum perforatum L.): A Review |
| title_full | St. John\'s wort (Hypericum perforatum L.): A Review |
| title_fullStr | St. John\'s wort (Hypericum perforatum L.): A Review |
| title_full_unstemmed | St. John\'s wort (Hypericum perforatum L.): A Review |
| title_short | St. John\'s wort (Hypericum perforatum L.): A Review |
| title_sort | st john s wort hypericum perforatum l a review |
| topic | st. john’s wort hypericin hypericin hyperforin depression |
| url | http://jmp.ir/article-1-683-en.html |
| work_keys_str_mv | AT hnaghdibadi stjohnsworthypericumperforatumlareview AT gamin stjohnsworthypericumperforatumlareview AT mmakkizadeh stjohnsworthypericumperforatumlareview AT saziai stjohnsworthypericumperforatumlareview |