MACC1 Regulates LGR5 to Promote Cancer Stem Cell Properties in Colorectal Cancer

MACC1 Regulates LGR5 to Promote Cancer Stem Cell Properties in Colorectal Cancer

Colorectal cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. The high mortality is directly associated with metastatic disease, which is thought to be initiated by colon cancer stem cells, according to the cancer stem cell (CSC) model. Consequently, early identification o...

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Bibliographic Details
Main Authors: Müge Erdem, Kyung Hwan Lee, Markus Hardt, Joseph L. Regan, Dennis Kobelt, Wolfgang Walther, Margarita Mokrizkij, Christian Regenbrecht, Ulrike Stein
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
MACC1
LGR5
transcriptional regulation
stemness
Online Access:https://www.mdpi.com/2072-6694/16/3/604

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