Essential Oil of <i>Lavandula officinalis</i>: Chemical Composition and Antibacterial Activities
The purpose of this study was to determine the chemical composition of the essential oil of <i>Lavandula officinalis</i> from Morocco using the GC-MS technique and assess the antibacterial effects against seven pathogenic bacteria strains isolated from the food origins of <i>Salmon...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/12/7/1571 |
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| author | Khaoula Diass Mohammed Merzouki Kaoutar Elfazazi Hanane Azzouzi Allal Challioui Khalil Azzaoui Belkheir Hammouti Rachid Touzani Flore Depeint Alicia Ayerdi Gotor Larbi Rhazi |
| author_facet | Khaoula Diass Mohammed Merzouki Kaoutar Elfazazi Hanane Azzouzi Allal Challioui Khalil Azzaoui Belkheir Hammouti Rachid Touzani Flore Depeint Alicia Ayerdi Gotor Larbi Rhazi |
| author_sort | Khaoula Diass |
| collection | DOAJ |
| description | The purpose of this study was to determine the chemical composition of the essential oil of <i>Lavandula officinalis</i> from Morocco using the GC-MS technique and assess the antibacterial effects against seven pathogenic bacteria strains isolated from the food origins of <i>Salmonella infantis</i>, <i>Salmonella kentucky</i>, <i>Salmonella newport,</i> three serotypes of <i>Escherichia coli</i> (O114H8K11, O127K88ac, O127H40K11) and <i>Klebsiella.</i> Tests of sensitivity were carried out on a solid surface using the Disc Diffusion Method. Results showed that <i>E. coli</i> and <i>S.newport</i> were sensitive to <i>Lavandula officinalis</i> essential oil. Minimum inhibitory concentrations (MIC) were determined using the method of agar dilution. The antibacterial results showed that four strains (three serotypes of <i>E. coli</i>, and <i>S. newport</i>) were remarkedly sensitive to <i>Lavandula officinalis</i> essential oil, giving MIC values of 88.7 µg/mL and 177.5 µg/mL. The molecular docking of the main oil products with the <i>E. coli</i> target protein 1VLY, showed that eucalyptol and linalyl acetate bind efficiently with the active site of the target protein. In particular, eucalyptol showed a higher activity than gentamicin used as positive control with a binding energy of −5.72 kcal/mol and −5.55 kcal/mol, respectively. |
| first_indexed | 2024-03-11T05:27:11Z |
| format | Article |
| id | doaj.art-d57669c0da614096ab9a60b7b36e0189 |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-11T05:27:11Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-d57669c0da614096ab9a60b7b36e01892023-11-17T17:24:30ZengMDPI AGPlants2223-77472023-04-01127157110.3390/plants12071571Essential Oil of <i>Lavandula officinalis</i>: Chemical Composition and Antibacterial ActivitiesKhaoula Diass0Mohammed Merzouki1Kaoutar Elfazazi2Hanane Azzouzi3Allal Challioui4Khalil Azzaoui5Belkheir Hammouti6Rachid Touzani7Flore Depeint8Alicia Ayerdi Gotor9Larbi Rhazi10Laboratory of Applied and Environmental Chemistry (LCAE), Faculty of Sciences, University Mohammed Premier, Oujda 60000, MoroccoLaboratoire de Chimie Appliquée et Environnement-Equipe Chimie Organique Macromoléculaire et Phytochimie, Faculté des Sciences, Université Mohammed Ier, Oujda 60000, MoroccoAgro-Food Technology and Quality Laboratory, Regional Center of Agricultural Research of Tadla, National Institute of Agricultural Research, Avenue Ennasr, BP 415 Rabat Principale, Rabat 10090, MoroccoAgro-Food Technology and Quality Laboratory, Regional Center of Agricultural Research of Tadla, National Institute of Agricultural Research, Avenue Ennasr, BP 415 Rabat Principale, Rabat 10090, MoroccoLaboratoire de Chimie Appliquée et Environnement-Equipe Chimie Organique Macromoléculaire et Phytochimie, Faculté des Sciences, Université Mohammed Ier, Oujda 60000, MoroccoLaboratory of Engineering, Electrochemistry, Modeling and Environment, Faculty of Sciences, Sidi Mohamed Ben Abdellah University, BP 1796, Fez 30050, MoroccoLaboratory of Industrial Engineering, Energy and The Environment (LI3E) SUPMTI, Rabat 10000, MoroccoLaboratory of Applied and Environmental Chemistry (LCAE), Faculty of Sciences, University Mohammed Premier, Oujda 60000, MoroccoInstitut Polytechnique UniLaSalle, Université d’Artois, ULR 7519, UniLaSalle, 19 rue Pierre Waguet, BP 30313, 60026 Beauvais, FranceInstitut Polytechnique UniLaSalle, AGHYLE, UP 2018.C101, UniLaSalle, 19 rue Pierre Waguet, BP 30313, 60026 Beauvais, FranceInstitut Polytechnique UniLaSalle, Université d’Artois, ULR 7519, UniLaSalle, 19 rue Pierre Waguet, BP 30313, 60026 Beauvais, FranceThe purpose of this study was to determine the chemical composition of the essential oil of <i>Lavandula officinalis</i> from Morocco using the GC-MS technique and assess the antibacterial effects against seven pathogenic bacteria strains isolated from the food origins of <i>Salmonella infantis</i>, <i>Salmonella kentucky</i>, <i>Salmonella newport,</i> three serotypes of <i>Escherichia coli</i> (O114H8K11, O127K88ac, O127H40K11) and <i>Klebsiella.</i> Tests of sensitivity were carried out on a solid surface using the Disc Diffusion Method. Results showed that <i>E. coli</i> and <i>S.newport</i> were sensitive to <i>Lavandula officinalis</i> essential oil. Minimum inhibitory concentrations (MIC) were determined using the method of agar dilution. The antibacterial results showed that four strains (three serotypes of <i>E. coli</i>, and <i>S. newport</i>) were remarkedly sensitive to <i>Lavandula officinalis</i> essential oil, giving MIC values of 88.7 µg/mL and 177.5 µg/mL. The molecular docking of the main oil products with the <i>E. coli</i> target protein 1VLY, showed that eucalyptol and linalyl acetate bind efficiently with the active site of the target protein. In particular, eucalyptol showed a higher activity than gentamicin used as positive control with a binding energy of −5.72 kcal/mol and −5.55 kcal/mol, respectively.https://www.mdpi.com/2223-7747/12/7/1571<i>Lavandula officinalis</i>essential oilantibacterial activitiesminimum inhibitory concentration (MIC)lavenderantimicrobial |
| spellingShingle | Khaoula Diass Mohammed Merzouki Kaoutar Elfazazi Hanane Azzouzi Allal Challioui Khalil Azzaoui Belkheir Hammouti Rachid Touzani Flore Depeint Alicia Ayerdi Gotor Larbi Rhazi Essential Oil of <i>Lavandula officinalis</i>: Chemical Composition and Antibacterial Activities Plants <i>Lavandula officinalis</i> essential oil antibacterial activities minimum inhibitory concentration (MIC) lavender antimicrobial |
| title | Essential Oil of <i>Lavandula officinalis</i>: Chemical Composition and Antibacterial Activities |
| title_full | Essential Oil of <i>Lavandula officinalis</i>: Chemical Composition and Antibacterial Activities |
| title_fullStr | Essential Oil of <i>Lavandula officinalis</i>: Chemical Composition and Antibacterial Activities |
| title_full_unstemmed | Essential Oil of <i>Lavandula officinalis</i>: Chemical Composition and Antibacterial Activities |
| title_short | Essential Oil of <i>Lavandula officinalis</i>: Chemical Composition and Antibacterial Activities |
| title_sort | essential oil of i lavandula officinalis i chemical composition and antibacterial activities |
| topic | <i>Lavandula officinalis</i> essential oil antibacterial activities minimum inhibitory concentration (MIC) lavender antimicrobial |
| url | https://www.mdpi.com/2223-7747/12/7/1571 |
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