Absence of IgG antibodies among high-risk contacts of two confirmed cases of Crimean-Congo haemorrhagic fever in the autonomous region of Madrid (Spain)
Crimean-Congo haemorrhagic fever (CCHF) is a widely distributed tick-borne disease. In Spain, the disease has emerged as outbreak associated with high-risk exposures. Our goal was to evaluate the prevalence of antibodies against the CCHF virus (CCHFV) in high-risk contacts. A cross-sectional study w...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-10-01
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| Series: | Journal of Infection and Public Health |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034120305967 |
| _version_ | 1819007762136301568 |
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| author | Pello Latasa Fernando de Ory José Ramón Arribas Maria Ángeles Sánchez-Uriz Ignacio Sanchez-Arcilla María Ordobás Anabel Negredo Elena Trigo Pilar Delgado Marco Marzola Maria Ángeles Lopaz María Paz Sánchez-Seco Fernando de la Calle-Prieto Pilar Ferrera Elena Rodriguez Alejandro Martín Maria Felipa del Cerro Esther Córdoba Marta Mora-Rillo Maria José Esteban |
| author_facet | Pello Latasa Fernando de Ory José Ramón Arribas Maria Ángeles Sánchez-Uriz Ignacio Sanchez-Arcilla María Ordobás Anabel Negredo Elena Trigo Pilar Delgado Marco Marzola Maria Ángeles Lopaz María Paz Sánchez-Seco Fernando de la Calle-Prieto Pilar Ferrera Elena Rodriguez Alejandro Martín Maria Felipa del Cerro Esther Córdoba Marta Mora-Rillo Maria José Esteban |
| author_sort | Pello Latasa |
| collection | DOAJ |
| description | Crimean-Congo haemorrhagic fever (CCHF) is a widely distributed tick-borne disease. In Spain, the disease has emerged as outbreak associated with high-risk exposures. Our goal was to evaluate the prevalence of antibodies against the CCHF virus (CCHFV) in high-risk contacts. A cross-sectional study was conducted. Three hundred eighty-six high-risk contacts were identified comprising family contacts and hospital workers who had attended the cases. Fifty-seven cases with closer exposure were selected. However, forty-nine cases participated in the study. IgG antibodies were detected by immunoenzymatic techniques. All determinations tested negative for anti-CCHFV IgG antibodies. Most of the responders were women (73.5%), and belong to the intensive care department (53.1%). In relation to other possible sources of exposures, 18.4% travelled to countries with CCHF transmission risk. No CCHF positivity was recorded among selected high-risk contacts. This highlights the importance of standard precautions which might have protected healthcare workers and care providers from CCHF infection. |
| first_indexed | 2024-12-21T00:29:44Z |
| format | Article |
| id | doaj.art-d578f040f10b45bd9a8baf0b6d48f9b2 |
| institution | Directory Open Access Journal |
| issn | 1876-0341 |
| language | English |
| last_indexed | 2024-12-21T00:29:44Z |
| publishDate | 2020-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Infection and Public Health |
| spelling | doaj.art-d578f040f10b45bd9a8baf0b6d48f9b22022-12-21T19:21:55ZengElsevierJournal of Infection and Public Health1876-03412020-10-01131015951598Absence of IgG antibodies among high-risk contacts of two confirmed cases of Crimean-Congo haemorrhagic fever in the autonomous region of Madrid (Spain)Pello Latasa0Fernando de Ory1José Ramón Arribas2Maria Ángeles Sánchez-Uriz3Ignacio Sanchez-Arcilla4María Ordobás5Anabel Negredo6Elena Trigo7Pilar Delgado8Marco Marzola9Maria Ángeles Lopaz10María Paz Sánchez-Seco11Fernando de la Calle-Prieto12Pilar Ferrera13Elena Rodriguez14Alejandro Martín15Maria Felipa del Cerro16Esther Córdoba17Marta Mora-Rillo18Maria José Esteban19Health Department of the Community of Madrid, Subdirectorate of Epidemiology, Madrid, Comunidad de Madrid, Spain; Corresponding author at: Consejería de Sanidad. Comunidad de Madrid, Dirección General de Salud Pública, Subdirección General de Epidemiología, C/ San Martín de Porres, 6, 28035 Madrid, Spain.Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Comunidad de Madrid, SpainLa Paz – Carlos III Universitary Hospital, High Level Isolation Unit, Madrid, Comunidad de Madrid, SpainInfanta Leonor Universitary Hospital, Occupational Risk Prevention Department, Madrid, Comunidad de Madrid, SpainGregorio Marañón Universitary Hospital, Occupational Risk Prevention Department, Madrid, Comunidad de Madrid, SpainHealth Department of the Community of Madrid, Subdirectorate of Epidemiology, Madrid, Comunidad de Madrid, SpainCentro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Comunidad de Madrid, SpainLa Paz – Carlos III Universitary Hospital, High Level Isolation Unit, Madrid, Comunidad de Madrid, SpainInfanta Leonor Universitary Hospital, Occupational Risk Prevention Department, Madrid, Comunidad de Madrid, SpainGregorio Marañón Universitary Hospital, Occupational Risk Prevention Department, Madrid, Comunidad de Madrid, SpainHealth Department of the Community of Madrid, Subdirectorate of Epidemiology, Madrid, Comunidad de Madrid, SpainCentro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Comunidad de Madrid, SpainLa Paz – Carlos III Universitary Hospital, High Level Isolation Unit, Madrid, Comunidad de Madrid, SpainInfanta Leonor Universitary Hospital, Occupational Risk Prevention Department, Madrid, Comunidad de Madrid, SpainHealth Department of the Community of Madrid, Subdirectorate of Epidemiology, Madrid, Comunidad de Madrid, SpainLa Paz – Carlos III Universitary Hospital, High Level Isolation Unit, Madrid, Comunidad de Madrid, SpainInfanta Leonor Universitary Hospital, Occupational Risk Prevention Department, Madrid, Comunidad de Madrid, SpainHealth Department of the Community of Madrid, Subdirectorate of Epidemiology, Madrid, Comunidad de Madrid, SpainLa Paz – Carlos III Universitary Hospital, High Level Isolation Unit, Madrid, Comunidad de Madrid, SpainHealth Department of the Community of Madrid, Subdirectorate of Epidemiology, Madrid, Comunidad de Madrid, SpainCrimean-Congo haemorrhagic fever (CCHF) is a widely distributed tick-borne disease. In Spain, the disease has emerged as outbreak associated with high-risk exposures. Our goal was to evaluate the prevalence of antibodies against the CCHF virus (CCHFV) in high-risk contacts. A cross-sectional study was conducted. Three hundred eighty-six high-risk contacts were identified comprising family contacts and hospital workers who had attended the cases. Fifty-seven cases with closer exposure were selected. However, forty-nine cases participated in the study. IgG antibodies were detected by immunoenzymatic techniques. All determinations tested negative for anti-CCHFV IgG antibodies. Most of the responders were women (73.5%), and belong to the intensive care department (53.1%). In relation to other possible sources of exposures, 18.4% travelled to countries with CCHF transmission risk. No CCHF positivity was recorded among selected high-risk contacts. This highlights the importance of standard precautions which might have protected healthcare workers and care providers from CCHF infection.http://www.sciencedirect.com/science/article/pii/S1876034120305967Health surveillanceInfectious disease transmissionSerologyCrimean-Congo haemorrhagic fever virusSpain |
| spellingShingle | Pello Latasa Fernando de Ory José Ramón Arribas Maria Ángeles Sánchez-Uriz Ignacio Sanchez-Arcilla María Ordobás Anabel Negredo Elena Trigo Pilar Delgado Marco Marzola Maria Ángeles Lopaz María Paz Sánchez-Seco Fernando de la Calle-Prieto Pilar Ferrera Elena Rodriguez Alejandro Martín Maria Felipa del Cerro Esther Córdoba Marta Mora-Rillo Maria José Esteban Absence of IgG antibodies among high-risk contacts of two confirmed cases of Crimean-Congo haemorrhagic fever in the autonomous region of Madrid (Spain) Journal of Infection and Public Health Health surveillance Infectious disease transmission Serology Crimean-Congo haemorrhagic fever virus Spain |
| title | Absence of IgG antibodies among high-risk contacts of two confirmed cases of Crimean-Congo haemorrhagic fever in the autonomous region of Madrid (Spain) |
| title_full | Absence of IgG antibodies among high-risk contacts of two confirmed cases of Crimean-Congo haemorrhagic fever in the autonomous region of Madrid (Spain) |
| title_fullStr | Absence of IgG antibodies among high-risk contacts of two confirmed cases of Crimean-Congo haemorrhagic fever in the autonomous region of Madrid (Spain) |
| title_full_unstemmed | Absence of IgG antibodies among high-risk contacts of two confirmed cases of Crimean-Congo haemorrhagic fever in the autonomous region of Madrid (Spain) |
| title_short | Absence of IgG antibodies among high-risk contacts of two confirmed cases of Crimean-Congo haemorrhagic fever in the autonomous region of Madrid (Spain) |
| title_sort | absence of igg antibodies among high risk contacts of two confirmed cases of crimean congo haemorrhagic fever in the autonomous region of madrid spain |
| topic | Health surveillance Infectious disease transmission Serology Crimean-Congo haemorrhagic fever virus Spain |
| url | http://www.sciencedirect.com/science/article/pii/S1876034120305967 |
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