Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial

<p>Abstract</p> <p>Background</p> <p>Multifamily group psychoeducation (MFG) has been shown to reduce relapse rates among individuals with first-episode psychosis. However, given the cognitive demands associated with participating in this intervention (e.g., learning an...

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Main Authors: Durst Linda, Peterson Rachele, Mai-Dixon Natalie, Moreno Francisco A, Breitborde Nicholas JK, Bernstein Beth, Byreddy Seenaiah, McFarlane William R
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Psychiatry
Online Access:http://www.biomedcentral.com/1471-244X/11/9
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author Durst Linda
Peterson Rachele
Mai-Dixon Natalie
Moreno Francisco A
Breitborde Nicholas JK
Bernstein Beth
Byreddy Seenaiah
McFarlane William R
author_facet Durst Linda
Peterson Rachele
Mai-Dixon Natalie
Moreno Francisco A
Breitborde Nicholas JK
Bernstein Beth
Byreddy Seenaiah
McFarlane William R
author_sort Durst Linda
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Multifamily group psychoeducation (MFG) has been shown to reduce relapse rates among individuals with first-episode psychosis. However, given the cognitive demands associated with participating in this intervention (e.g., learning and applying a structured problem-solving activity), the cognitive deficits that accompany psychotic disorders may limit the ability of certain individuals to benefit from this intervention. Thus, the goal of this study is to examine whether individuals with first-episode psychosis who participate simultaneously in MFG and cognitive remediation--an intervention shown to improve cognitive functioning among individuals with psychotic disorders--will be less likely to experience a relapse than individuals who participate in MFG alone.</p> <p>Methods/Design</p> <p>Forty individuals with first-episode psychosis and their caregiving relative will be recruited to participate in this study. Individuals with first-episode psychosis will be randomized to one of two conditions: (i) MFG with concurrent participation in cognitive remediation or (ii) MFG alone. The primary outcome for this study is relapse of psychotic symptoms. We will also examine secondary outcomes among both individuals with first-episode psychosis (i.e., social and vocational functioning, health-related quality of life, service utilization, independent living status, and cognitive functioning) and their caregiving relatives (i.e., caregiver burden, anxiety, and depression)</p> <p>Discussion</p> <p>Cognitive remediation offers the possibility of ameliorating a specific deficit (i.e., deficits in cognitive functioning) that often accompanies psychotic symptoms and may restrict the magnitude of the clinical benefits derived from MFG.</p> <p>Trial Registration</p> <p>ClinicalTrials (NCT): <a href="http://www.clinicaltrials.gov/ct2/show/NCT01196286">NCT01196286</a></p>
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spelling doaj.art-d57e31c2c2c4495bb615baab3a19cda72022-12-22T02:13:04ZengBMCBMC Psychiatry1471-244X2011-01-01111910.1186/1471-244X-11-9Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled TrialDurst LindaPeterson RacheleMai-Dixon NatalieMoreno Francisco ABreitborde Nicholas JKBernstein BethByreddy SeenaiahMcFarlane William R<p>Abstract</p> <p>Background</p> <p>Multifamily group psychoeducation (MFG) has been shown to reduce relapse rates among individuals with first-episode psychosis. However, given the cognitive demands associated with participating in this intervention (e.g., learning and applying a structured problem-solving activity), the cognitive deficits that accompany psychotic disorders may limit the ability of certain individuals to benefit from this intervention. Thus, the goal of this study is to examine whether individuals with first-episode psychosis who participate simultaneously in MFG and cognitive remediation--an intervention shown to improve cognitive functioning among individuals with psychotic disorders--will be less likely to experience a relapse than individuals who participate in MFG alone.</p> <p>Methods/Design</p> <p>Forty individuals with first-episode psychosis and their caregiving relative will be recruited to participate in this study. Individuals with first-episode psychosis will be randomized to one of two conditions: (i) MFG with concurrent participation in cognitive remediation or (ii) MFG alone. The primary outcome for this study is relapse of psychotic symptoms. We will also examine secondary outcomes among both individuals with first-episode psychosis (i.e., social and vocational functioning, health-related quality of life, service utilization, independent living status, and cognitive functioning) and their caregiving relatives (i.e., caregiver burden, anxiety, and depression)</p> <p>Discussion</p> <p>Cognitive remediation offers the possibility of ameliorating a specific deficit (i.e., deficits in cognitive functioning) that often accompanies psychotic symptoms and may restrict the magnitude of the clinical benefits derived from MFG.</p> <p>Trial Registration</p> <p>ClinicalTrials (NCT): <a href="http://www.clinicaltrials.gov/ct2/show/NCT01196286">NCT01196286</a></p>http://www.biomedcentral.com/1471-244X/11/9
spellingShingle Durst Linda
Peterson Rachele
Mai-Dixon Natalie
Moreno Francisco A
Breitborde Nicholas JK
Bernstein Beth
Byreddy Seenaiah
McFarlane William R
Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial
BMC Psychiatry
title Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial
title_full Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial
title_fullStr Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial
title_full_unstemmed Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial
title_short Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial
title_sort multifamily group psychoeducation and cognitive remediation for first episode psychosis a randomized controlled trial
url http://www.biomedcentral.com/1471-244X/11/9
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