Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action
Bioactive peptides are a group of biological molecules that are normally buried in the structure of parent proteins and become active after the cleavage of the proteins. Another group of peptides is actively produced and found in many microorganisms and the body of organisms. Today, many groups of b...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/23/3/1445 |
| _version_ | 1797487405197950976 |
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| author | Mohsen Akbarian Ali Khani Sara Eghbalpour Vladimir N. Uversky |
| author_facet | Mohsen Akbarian Ali Khani Sara Eghbalpour Vladimir N. Uversky |
| author_sort | Mohsen Akbarian |
| collection | DOAJ |
| description | Bioactive peptides are a group of biological molecules that are normally buried in the structure of parent proteins and become active after the cleavage of the proteins. Another group of peptides is actively produced and found in many microorganisms and the body of organisms. Today, many groups of bioactive peptides have been marketed chemically or recombinantly. This article reviews the various production methods and sources of these important/ubiquitous and useful biomolecules. Their applications, such as antimicrobial, antihypertensive, antioxidant activities, blood-lipid-lowering effect, opioid role, antiobesity, ability to bind minerals, antidiabetic, and antiaging effects, will be explored. The types of pathways proposed for bioactive applications will be in the next part of the article, and at the end, the future perspectives of bioactive peptides will be reviewed. Reading this article is recommended for researchers interested in various fields of physiology, microbiology, biochemistry, and nanotechnology and food industry professionals. |
| first_indexed | 2024-03-09T23:48:11Z |
| format | Article |
| id | doaj.art-d58172d94aa04a5a90846ed4892a94ad |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T23:48:11Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-d58172d94aa04a5a90846ed4892a94ad2023-11-23T16:40:34ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-01-01233144510.3390/ijms23031445Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of ActionMohsen Akbarian0Ali Khani1Sara Eghbalpour2Vladimir N. Uversky3Department of Chemistry, National Cheng Kung University, Tainan 701, TaiwanDepartment of Radiation Sciences, Faculty of Applied Medicine, Iran University of Medical Sciences, Tehran 1449614535, IranDepartment of Obstetrics and Gynecology Surgery, Babol University of Medical Sciences, Babol 4717647745, IranDepartment of Molecular Medicine and Health Byrd Alzheimer’s Institute, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USABioactive peptides are a group of biological molecules that are normally buried in the structure of parent proteins and become active after the cleavage of the proteins. Another group of peptides is actively produced and found in many microorganisms and the body of organisms. Today, many groups of bioactive peptides have been marketed chemically or recombinantly. This article reviews the various production methods and sources of these important/ubiquitous and useful biomolecules. Their applications, such as antimicrobial, antihypertensive, antioxidant activities, blood-lipid-lowering effect, opioid role, antiobesity, ability to bind minerals, antidiabetic, and antiaging effects, will be explored. The types of pathways proposed for bioactive applications will be in the next part of the article, and at the end, the future perspectives of bioactive peptides will be reviewed. Reading this article is recommended for researchers interested in various fields of physiology, microbiology, biochemistry, and nanotechnology and food industry professionals.https://www.mdpi.com/1422-0067/23/3/1445bioactive peptidesproduction of peptidesapplication of peptidesmechanism of application |
| spellingShingle | Mohsen Akbarian Ali Khani Sara Eghbalpour Vladimir N. Uversky Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action International Journal of Molecular Sciences bioactive peptides production of peptides application of peptides mechanism of application |
| title | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
| title_full | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
| title_fullStr | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
| title_full_unstemmed | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
| title_short | Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action |
| title_sort | bioactive peptides synthesis sources applications and proposed mechanisms of action |
| topic | bioactive peptides production of peptides application of peptides mechanism of application |
| url | https://www.mdpi.com/1422-0067/23/3/1445 |
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