Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses
Background: Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2021-01-01
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| Series: | European Journal of Psychotraumatology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/20008198.2021.1930690 |
| _version_ | 1827964930567962624 |
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| author | Eirini Karyotaki Marit Sijbrandij Marianna Purgato Ceren Acarturk Daniel Lakin Della Bailey Emily Peckham Ersin Uygun Federico Tedeschi Johannes Wancata Jura Augustinavicius Ken Carswell Maritta Välimäki Mark van Ommeren Markus Koesters Mariana Popa Marx Ronald Leku Minna Anttila Rachel Churchill Ross White Sarah Al-Hashimi Tella Lantta Teresa Au Thomas Klein Wietse A. Tol Pim Cuijpers Corrado Barbui |
| author_facet | Eirini Karyotaki Marit Sijbrandij Marianna Purgato Ceren Acarturk Daniel Lakin Della Bailey Emily Peckham Ersin Uygun Federico Tedeschi Johannes Wancata Jura Augustinavicius Ken Carswell Maritta Välimäki Mark van Ommeren Markus Koesters Mariana Popa Marx Ronald Leku Minna Anttila Rachel Churchill Ross White Sarah Al-Hashimi Tella Lantta Teresa Au Thomas Klein Wietse A. Tol Pim Cuijpers Corrado Barbui |
| author_sort | Eirini Karyotaki |
| collection | DOAJ |
| description | Background: Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals. |
| first_indexed | 2024-04-09T17:24:18Z |
| format | Article |
| id | doaj.art-d582913e76a84d36a3ce82891a82b110 |
| institution | Directory Open Access Journal |
| issn | 2000-8066 |
| language | English |
| last_indexed | 2024-04-09T17:24:18Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | European Journal of Psychotraumatology |
| spelling | doaj.art-d582913e76a84d36a3ce82891a82b1102023-04-18T14:59:10ZengTaylor & Francis GroupEuropean Journal of Psychotraumatology2000-80662021-01-0112110.1080/20008198.2021.19306901930690Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analysesEirini Karyotaki0Marit Sijbrandij1Marianna Purgato2Ceren Acarturk3Daniel Lakin4Della Bailey5Emily Peckham6Ersin Uygun7Federico Tedeschi8Johannes Wancata9Jura Augustinavicius10Ken Carswell11Maritta Välimäki12Mark van Ommeren13Markus Koesters14Mariana Popa15Marx Ronald Leku16Minna Anttila17Rachel Churchill18Ross White19Sarah Al-Hashimi20Tella Lantta21Teresa Au22Thomas Klein23Wietse A. Tol24Pim Cuijpers25Corrado Barbui26Vrije Universiteit AmsterdamVrije Universiteit AmsterdamUniversity of VeronaKoc UniversityBloomberg School of Public Health, Johns Hopkins UniversityUniversity of YorkUniversity of YorkBilgi UniversityUniversity of VeronaMedical University of ViennaBloomberg School of Public Health, Johns Hopkins UniversityWorld Health OrganizationUniversity of TurkuWorld Health OrganizationUlm UniversityUniversity of LiverpoolHealthRight UgandaUniversity of TurkuUniversity of YorkUniversity of LiverpoolMedical University of ViennaUniversity of TurkuWorld Health OrganizationUlm UniversityBloomberg School of Public Health, Johns Hopkins UniversityVrije Universiteit AmsterdamUniversity of VeronaBackground: Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals.http://dx.doi.org/10.1080/20008198.2021.1930690refugeesasylum seekersindividual participant datadepressioncommon mental disorders |
| spellingShingle | Eirini Karyotaki Marit Sijbrandij Marianna Purgato Ceren Acarturk Daniel Lakin Della Bailey Emily Peckham Ersin Uygun Federico Tedeschi Johannes Wancata Jura Augustinavicius Ken Carswell Maritta Välimäki Mark van Ommeren Markus Koesters Mariana Popa Marx Ronald Leku Minna Anttila Rachel Churchill Ross White Sarah Al-Hashimi Tella Lantta Teresa Au Thomas Klein Wietse A. Tol Pim Cuijpers Corrado Barbui Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses European Journal of Psychotraumatology refugees asylum seekers individual participant data depression common mental disorders |
| title | Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses |
| title_full | Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses |
| title_fullStr | Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses |
| title_full_unstemmed | Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses |
| title_short | Self-help plus for refugees and asylum seekers; study protocol for a series of individual participant data meta-analyses |
| title_sort | self help plus for refugees and asylum seekers study protocol for a series of individual participant data meta analyses |
| topic | refugees asylum seekers individual participant data depression common mental disorders |
| url | http://dx.doi.org/10.1080/20008198.2021.1930690 |
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