Application of a Novel Au@ZIF-8 Composite in the Detection of Bisphenol A by Surface-Enhanced Raman Spectroscopy

Bisphenol A (BPA) is an endocrine disruptor which is widely present in fish under the influence of environmental pollution. It is essential to establish a rapid detection method for BPA. Zeolitic imidazolate framework (ZIF-8) is a typical metal-organic framework material (MOFs) with a strong adsorpt...

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Main Authors: Yunfei Xie, Xianghui Dong, Nifei Cai, Fangwei Yang, Weirong Yao, Lijun Huang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/12/4/813
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author Yunfei Xie
Xianghui Dong
Nifei Cai
Fangwei Yang
Weirong Yao
Lijun Huang
author_facet Yunfei Xie
Xianghui Dong
Nifei Cai
Fangwei Yang
Weirong Yao
Lijun Huang
author_sort Yunfei Xie
collection DOAJ
description Bisphenol A (BPA) is an endocrine disruptor which is widely present in fish under the influence of environmental pollution. It is essential to establish a rapid detection method for BPA. Zeolitic imidazolate framework (ZIF-8) is a typical metal-organic framework material (MOFs) with a strong adsorption capacity, which can effectively adsorb harmful substances in food. Combining MOFs and surface-enhanced Raman spectroscopy (SERS) can achieve rapid and accurate screening of toxic substances. In this study, a rapid detection method for BPA was established by preparing a new reinforced substrate Au@ZIF-8. The SERS detection method was optimized by combining SERS technology with ZIF-8. The Raman peak at 1172 cm<sup>−1</sup> was used as the characteristic quantitative peak, and the lowest detection concentration of BPA was as low as 0.1 mg/L. In the concentration range of 0.1~10 mg/L, the linear relationship between SERS peak intensity and the concentration of BPA was good, and R<sup>2</sup> was 0.9954. This novel SERS substrate was proven to have great potential in rapidly detecting BPA in food.
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spelling doaj.art-d58341199f994d22b0289ca2beaebe672023-11-16T20:30:53ZengMDPI AGFoods2304-81582023-02-0112481310.3390/foods12040813Application of a Novel Au@ZIF-8 Composite in the Detection of Bisphenol A by Surface-Enhanced Raman SpectroscopyYunfei Xie0Xianghui Dong1Nifei Cai2Fangwei Yang3Weirong Yao4Lijun Huang5State Key Laboratory of Food Science and Technology, Jiangnan University, No. 1800 Lihu Avenue, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, Jiangnan University, No. 1800 Lihu Avenue, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, Jiangnan University, No. 1800 Lihu Avenue, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, Jiangnan University, No. 1800 Lihu Avenue, Wuxi 214122, ChinaState Key Laboratory of Food Science and Technology, Jiangnan University, No. 1800 Lihu Avenue, Wuxi 214122, ChinaWuxi Food Safety Inspection and Test Center, 35-210 Changjiang South Road, Wuxi 214142, ChinaBisphenol A (BPA) is an endocrine disruptor which is widely present in fish under the influence of environmental pollution. It is essential to establish a rapid detection method for BPA. Zeolitic imidazolate framework (ZIF-8) is a typical metal-organic framework material (MOFs) with a strong adsorption capacity, which can effectively adsorb harmful substances in food. Combining MOFs and surface-enhanced Raman spectroscopy (SERS) can achieve rapid and accurate screening of toxic substances. In this study, a rapid detection method for BPA was established by preparing a new reinforced substrate Au@ZIF-8. The SERS detection method was optimized by combining SERS technology with ZIF-8. The Raman peak at 1172 cm<sup>−1</sup> was used as the characteristic quantitative peak, and the lowest detection concentration of BPA was as low as 0.1 mg/L. In the concentration range of 0.1~10 mg/L, the linear relationship between SERS peak intensity and the concentration of BPA was good, and R<sup>2</sup> was 0.9954. This novel SERS substrate was proven to have great potential in rapidly detecting BPA in food.https://www.mdpi.com/2304-8158/12/4/813SERSmetal-organic frameworksbisphenol Arapid detection
spellingShingle Yunfei Xie
Xianghui Dong
Nifei Cai
Fangwei Yang
Weirong Yao
Lijun Huang
Application of a Novel Au@ZIF-8 Composite in the Detection of Bisphenol A by Surface-Enhanced Raman Spectroscopy
Foods
SERS
metal-organic frameworks
bisphenol A
rapid detection
title Application of a Novel Au@ZIF-8 Composite in the Detection of Bisphenol A by Surface-Enhanced Raman Spectroscopy
title_full Application of a Novel Au@ZIF-8 Composite in the Detection of Bisphenol A by Surface-Enhanced Raman Spectroscopy
title_fullStr Application of a Novel Au@ZIF-8 Composite in the Detection of Bisphenol A by Surface-Enhanced Raman Spectroscopy
title_full_unstemmed Application of a Novel Au@ZIF-8 Composite in the Detection of Bisphenol A by Surface-Enhanced Raman Spectroscopy
title_short Application of a Novel Au@ZIF-8 Composite in the Detection of Bisphenol A by Surface-Enhanced Raman Spectroscopy
title_sort application of a novel au zif 8 composite in the detection of bisphenol a by surface enhanced raman spectroscopy
topic SERS
metal-organic frameworks
bisphenol A
rapid detection
url https://www.mdpi.com/2304-8158/12/4/813
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