Symptomatic Popliteal Artery Aneurysms in Recently SARS-CoV-2-Infected Patients: The Microangiopathic Thrombosis That Undermines Treatment
Background: Arterial and venous thrombosis are complications in SARS-CoV-2-infected patients. The microangiopathic thrombosis in affected patients can compromise results in urgent limb revascularizations. Aim of our study is to report on the incidence of symptoms development in patients affected by...
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| Format: | Article |
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MDPI AG
2023-02-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/13/4/647 |
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| author | Laura Capoccia Wassim Mansour Luca di Marzo Sabrina Grimaldi Alessia Di Girolamo |
| author_facet | Laura Capoccia Wassim Mansour Luca di Marzo Sabrina Grimaldi Alessia Di Girolamo |
| author_sort | Laura Capoccia |
| collection | DOAJ |
| description | Background: Arterial and venous thrombosis are complications in SARS-CoV-2-infected patients. The microangiopathic thrombosis in affected patients can compromise results in urgent limb revascularizations. Aim of our study is to report on the incidence of symptoms development in patients affected by popliteal artery aneurysm (PAA) and to analyze the effect of COVID-19 infection on outcomes. Methods: Data on patients surgically treated for PAA from the massive widespread of COVID-19 vaccine (March 2021) to March 2022 were prospectively collected. Factors considered for analysis were: presence of symptoms, aneurysm diameter and length, time from symptom onset and hospital referral, ongoing or recently COVID-19 infection. Outcomes measures were: death, amputation, and neurological deficit. Results: Between March 2021 and March 2022, 35 patients were surgically treated for PAA. Among them 15 referred to our hospital for symptomatic PAA and were urgently treated. Urgent treatments included both endovascular procedures and open surgeries. Nine out of 15 symptomatic patients had an ongoing or recently recovered COVID-19 infection. COVID-19 infection was strongly associated to symptoms development in patients affected by PAA and to surgical failure in those patients (OR 40, 95% CI 2.01–794.31, <i>p</i> = 0.005). Conclusion: In our series, presence of COVID-19 infection was strongly associated to ischemic symptoms onset and to complications after urgent treatment in symptomatic patients. |
| first_indexed | 2024-03-11T08:57:22Z |
| format | Article |
| id | doaj.art-d584142d0c0647ca97e1376c4a31f667 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-11T08:57:22Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-d584142d0c0647ca97e1376c4a31f6672023-11-16T20:00:55ZengMDPI AGDiagnostics2075-44182023-02-0113464710.3390/diagnostics13040647Symptomatic Popliteal Artery Aneurysms in Recently SARS-CoV-2-Infected Patients: The Microangiopathic Thrombosis That Undermines TreatmentLaura Capoccia0Wassim Mansour1Luca di Marzo2Sabrina Grimaldi3Alessia Di Girolamo4Department of Surgery, Vascular Surgery Division, SS Filippo e Nicola Hospital, 67051 Avezzano, ItalyDepartment of General Surgery and Specialist Surgery, Sapienza University of Rome, Policlinico Umberto I of Rome, Viale del Policlinico 155, 00162 Rome, ItalyDepartment of General Surgery and Specialist Surgery, Sapienza University of Rome, Policlinico Umberto I of Rome, Viale del Policlinico 155, 00162 Rome, ItalyDepartment of General Surgery and Specialist Surgery, Sapienza University of Rome, Policlinico Umberto I of Rome, Viale del Policlinico 155, 00162 Rome, ItalyDepartment of General Surgery and Specialist Surgery, Sapienza University of Rome, Policlinico Umberto I of Rome, Viale del Policlinico 155, 00162 Rome, ItalyBackground: Arterial and venous thrombosis are complications in SARS-CoV-2-infected patients. The microangiopathic thrombosis in affected patients can compromise results in urgent limb revascularizations. Aim of our study is to report on the incidence of symptoms development in patients affected by popliteal artery aneurysm (PAA) and to analyze the effect of COVID-19 infection on outcomes. Methods: Data on patients surgically treated for PAA from the massive widespread of COVID-19 vaccine (March 2021) to March 2022 were prospectively collected. Factors considered for analysis were: presence of symptoms, aneurysm diameter and length, time from symptom onset and hospital referral, ongoing or recently COVID-19 infection. Outcomes measures were: death, amputation, and neurological deficit. Results: Between March 2021 and March 2022, 35 patients were surgically treated for PAA. Among them 15 referred to our hospital for symptomatic PAA and were urgently treated. Urgent treatments included both endovascular procedures and open surgeries. Nine out of 15 symptomatic patients had an ongoing or recently recovered COVID-19 infection. COVID-19 infection was strongly associated to symptoms development in patients affected by PAA and to surgical failure in those patients (OR 40, 95% CI 2.01–794.31, <i>p</i> = 0.005). Conclusion: In our series, presence of COVID-19 infection was strongly associated to ischemic symptoms onset and to complications after urgent treatment in symptomatic patients.https://www.mdpi.com/2075-4418/13/4/647popliteal artery aneurysmendovascular treatmentCOVID-19thrombosisfemoro-popliteal bypass |
| spellingShingle | Laura Capoccia Wassim Mansour Luca di Marzo Sabrina Grimaldi Alessia Di Girolamo Symptomatic Popliteal Artery Aneurysms in Recently SARS-CoV-2-Infected Patients: The Microangiopathic Thrombosis That Undermines Treatment Diagnostics popliteal artery aneurysm endovascular treatment COVID-19 thrombosis femoro-popliteal bypass |
| title | Symptomatic Popliteal Artery Aneurysms in Recently SARS-CoV-2-Infected Patients: The Microangiopathic Thrombosis That Undermines Treatment |
| title_full | Symptomatic Popliteal Artery Aneurysms in Recently SARS-CoV-2-Infected Patients: The Microangiopathic Thrombosis That Undermines Treatment |
| title_fullStr | Symptomatic Popliteal Artery Aneurysms in Recently SARS-CoV-2-Infected Patients: The Microangiopathic Thrombosis That Undermines Treatment |
| title_full_unstemmed | Symptomatic Popliteal Artery Aneurysms in Recently SARS-CoV-2-Infected Patients: The Microangiopathic Thrombosis That Undermines Treatment |
| title_short | Symptomatic Popliteal Artery Aneurysms in Recently SARS-CoV-2-Infected Patients: The Microangiopathic Thrombosis That Undermines Treatment |
| title_sort | symptomatic popliteal artery aneurysms in recently sars cov 2 infected patients the microangiopathic thrombosis that undermines treatment |
| topic | popliteal artery aneurysm endovascular treatment COVID-19 thrombosis femoro-popliteal bypass |
| url | https://www.mdpi.com/2075-4418/13/4/647 |
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