MiR-4521 perturbs FOXM1-mediated DNA damage response in breast cancer

MiR-4521 perturbs FOXM1-mediated DNA damage response in breast cancer

Introduction: Forkhead (FOX) transcription factors are involved in cell cycle control, cellular differentiation, maintenance of tissues, and aging. Mutation or aberrant expression of FOX proteins is associated with developmental disorders and cancers. FOXM1, an oncogenic transcription factor, is a p...

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Main Authors: Raviprasad Kuthethur, Divya Adiga, Amoolya Kandettu, Maria Sona Jerome, Sandeep Mallya, Kamalesh Dattaram Mumbrekar, Shama Prasada Kabekkodu, Sanjiban Chakrabarty
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
breast cancer
miR-4521
FoxM1
DNA damage
cell cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1131433/full

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