572 PYX-102, an anti-KLRG1 antibody, enhances cytotoxic activity of CD8-T-cells from PBMC and human tumor samples by blocking the interaction between KLRG1 and cadherins
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2023-11-01
|
Series: | Journal for ImmunoTherapy of Cancer |
_version_ | 1827764932330913792 |
---|---|
author | Ronald Herbst Anthony Rodriguez Kei Yasuda Philipp Steiner Liyang Diao Jianwen Feng Matthew Iovino Sara Lewandowski Dan Felitsky Ben Keller Ona Miller Alyssa Quigley Jan Pinkas |
author_facet | Ronald Herbst Anthony Rodriguez Kei Yasuda Philipp Steiner Liyang Diao Jianwen Feng Matthew Iovino Sara Lewandowski Dan Felitsky Ben Keller Ona Miller Alyssa Quigley Jan Pinkas |
author_sort | Ronald Herbst |
collection | DOAJ |
first_indexed | 2024-03-11T11:12:54Z |
format | Article |
id | doaj.art-d58746e935aa484e91284e907bc0b59c |
institution | Directory Open Access Journal |
issn | 2051-1426 |
language | English |
last_indexed | 2024-03-11T11:12:54Z |
publishDate | 2023-11-01 |
publisher | BMJ Publishing Group |
record_format | Article |
series | Journal for ImmunoTherapy of Cancer |
spelling | doaj.art-d58746e935aa484e91284e907bc0b59c2023-11-11T17:00:08ZengBMJ Publishing GroupJournal for ImmunoTherapy of Cancer2051-14262023-11-0111Suppl 110.1136/jitc-2023-SITC2023.0572572 PYX-102, an anti-KLRG1 antibody, enhances cytotoxic activity of CD8-T-cells from PBMC and human tumor samples by blocking the interaction between KLRG1 and cadherinsRonald Herbst0Anthony Rodriguez1Kei Yasuda2Philipp Steiner3Liyang Diao4Jianwen Feng5Matthew Iovino6Sara Lewandowski7Dan Felitsky8Ben Keller9Ona Miller10Alyssa Quigley11Jan Pinkas12Aff162 grid.418152.bMedimmune Gaithersburg MD USAAff573 grid.27755.32000000009136933XUniversity of Virginia Charlottesville VA USA1Renal SectionWerewolf Therapeutics, Cambridge, MA, United StatesPyxis Oncology, Boston, MA, USAPyxis Oncology, Boston, MA, USAPyxis Oncology, Boston, MA, USAPyxis Oncology, Boston, MA, USAPyxis Oncology, Boston, MA, USAPyxis Oncology, Boston, MA, USAPyxis Oncology, Boston, MA, USAPyxis Oncology, Boston, MA, USAPyxis Oncology, Boston, MA, USA |
spellingShingle | Ronald Herbst Anthony Rodriguez Kei Yasuda Philipp Steiner Liyang Diao Jianwen Feng Matthew Iovino Sara Lewandowski Dan Felitsky Ben Keller Ona Miller Alyssa Quigley Jan Pinkas 572 PYX-102, an anti-KLRG1 antibody, enhances cytotoxic activity of CD8-T-cells from PBMC and human tumor samples by blocking the interaction between KLRG1 and cadherins Journal for ImmunoTherapy of Cancer |
title | 572 PYX-102, an anti-KLRG1 antibody, enhances cytotoxic activity of CD8-T-cells from PBMC and human tumor samples by blocking the interaction between KLRG1 and cadherins |
title_full | 572 PYX-102, an anti-KLRG1 antibody, enhances cytotoxic activity of CD8-T-cells from PBMC and human tumor samples by blocking the interaction between KLRG1 and cadherins |
title_fullStr | 572 PYX-102, an anti-KLRG1 antibody, enhances cytotoxic activity of CD8-T-cells from PBMC and human tumor samples by blocking the interaction between KLRG1 and cadherins |
title_full_unstemmed | 572 PYX-102, an anti-KLRG1 antibody, enhances cytotoxic activity of CD8-T-cells from PBMC and human tumor samples by blocking the interaction between KLRG1 and cadherins |
title_short | 572 PYX-102, an anti-KLRG1 antibody, enhances cytotoxic activity of CD8-T-cells from PBMC and human tumor samples by blocking the interaction between KLRG1 and cadherins |
title_sort | 572 pyx 102 an anti klrg1 antibody enhances cytotoxic activity of cd8 t cells from pbmc and human tumor samples by blocking the interaction between klrg1 and cadherins |
work_keys_str_mv | AT ronaldherbst 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT anthonyrodriguez 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT keiyasuda 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT philippsteiner 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT liyangdiao 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT jianwenfeng 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT matthewiovino 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT saralewandowski 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT danfelitsky 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT benkeller 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT onamiller 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT alyssaquigley 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins AT janpinkas 572pyx102anantiklrg1antibodyenhancescytotoxicactivityofcd8tcellsfrompbmcandhumantumorsamplesbyblockingtheinteractionbetweenklrg1andcadherins |