Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum

Using a self-generated hypoxic assay, we show that the amoeba Dictyostelium discoideum displays a remarkable collective aerotactic behavior. When a cell colony is covered, cells quickly consume the available oxygen (O2) and form a dense ring moving outwards at constant speed and density. To decipher...

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Bibliographic Details
Main Authors: Olivier Cochet-Escartin, Mete Demircigil, Satomi Hirose, Blandine Allais, Philippe Gonzalo, Ivan Mikaelian, Kenichi Funamoto, Christophe Anjard, Vincent Calvez, Jean-Paul Rieu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-08-01
Series:eLife
Subjects:
hypoxia
self-generated gradients
chemotaxis
collective migration
oxygen sensing
Online Access:https://elifesciences.org/articles/64731

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