A Simple and High-Throughput Analysis of Amatoxins and Phallotoxins in Human Plasma, Serum and Urine Using UPLC-MS/MS Combined with PRiME HLB μElution Platform

A Simple and High-Throughput Analysis of Amatoxins and Phallotoxins in Human Plasma, Serum and Urine Using UPLC-MS/MS Combined with PRiME HLB μElution Platform

Amatoxins and phallotoxins are toxic cyclopeptides found in the genus Amanita and are among the predominant causes of fatal food poisoning in China. In the treatment of Amanita mushroom poisoning, an early and definite diagnosis is necessary for a successful outcome, which has prompted the developme...

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Bibliographic Details
Main Authors: Shuo Zhang, Yunfeng Zhao, Haijiao Li, Shuang Zhou, Dawei Chen, Yizhe Zhang, Qunmei Yao, Chengye Sun
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Toxins
Subjects:
poisonous mushroom
amatoxin
phallotoxin
PRiME HLB
μElution
LC-MS/MS
biological fluids
Online Access:http://www.mdpi.com/2072-6651/8/5/128

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