Detection of replication-defective hepatitis A virus based on the correlation between real-time polymerase chain reaction and ELISA in situ results

ELISA in situ can be used to titrate hepatitis A virus (HAV) particles and real-time polymerase chain reaction (RT-PCR) has been shown to be a fast method to quantify the HAV genome. Precise quantification of viral concentration is necessary to distinguish between infectious and non-infectious parti...

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Bibliographic Details
Main Authors: Alyne Moraes Costa, Luciane Almeida Amado, Vanessa Salete de Paula
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2013-02-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000100006