Orofacial tuberculosis: A diagnostic challenge

Tuberculosis is typically a pulmonary chronic infectious disease with a high prevalence in developing countries which carries a substantial rate of mortality. Extrapulmonary disease may occur, mainly second to the endogenous spread of the pathogen from the primary site. Oral or mandibular involvemen...

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Main Authors: Sabah Abdulaziz Issa, Hussein Ali Abdulnabi, Mustafa Emaduldeen Jameel
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:IDCases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250920301335
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author Sabah Abdulaziz Issa
Hussein Ali Abdulnabi
Mustafa Emaduldeen Jameel
author_facet Sabah Abdulaziz Issa
Hussein Ali Abdulnabi
Mustafa Emaduldeen Jameel
author_sort Sabah Abdulaziz Issa
collection DOAJ
description Tuberculosis is typically a pulmonary chronic infectious disease with a high prevalence in developing countries which carries a substantial rate of mortality. Extrapulmonary disease may occur, mainly second to the endogenous spread of the pathogen from the primary site. Oral or mandibular involvement represents a minority among the reported cases. A 12-year-old female patient with a diffuse left-sided facial swelling and dull pain that gradually developed over 8 months, presented to us with misdiagnosis and poor management. Examination was found to have a firm swelling involving the buccal region, and left posterior mandible with intact overlying skin and mucosa, and palpable cervical lymphadenopathy. Imaging showed a heterogeneous osteolytic lesion of left ramus extending to the surrounding soft tissue. The diagnosis with oro-facial tuberculosis was established by histopathological study and confirmed by the Mantoux test and polymerase chain reaction. Although it occurs rarely, oro-facial tuberculosis has detrimental local and systemic effects, and devoid of characteristic clinical and radiographic features, poses a diagnostic challenge.
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spelling doaj.art-d58e8e789dff446fafe7a6dab1e70dd82022-12-21T22:23:02ZengElsevierIDCases2214-25092020-01-0121e00825Orofacial tuberculosis: A diagnostic challengeSabah Abdulaziz Issa0Hussein Ali Abdulnabi1Mustafa Emaduldeen Jameel2Consultant Oral and Maxillofacial Surgeon, Department of Oral and Maxillofacial Surgery, Medical City Complex, Bab Al Muadham, 10047, Baghdad, IraqOral and Maxillofacial Surgery Board Resident, Department of Oral and Maxillofacial Surgery, Medical City Complex, Bab Al Muadham, 10047, Baghdad, Iraq; Corresponding author at: Department of Oral and Maxillofacial Surgery, Medical City Complex, Bab Al Muadham, 10047, Baghdad, Iraq.Oral and Maxillofacial Surgery Board Resident, Department of Oral and Maxillofacial Surgery, Medical City Complex, Bab Al Muadham, 10047, Baghdad, IraqTuberculosis is typically a pulmonary chronic infectious disease with a high prevalence in developing countries which carries a substantial rate of mortality. Extrapulmonary disease may occur, mainly second to the endogenous spread of the pathogen from the primary site. Oral or mandibular involvement represents a minority among the reported cases. A 12-year-old female patient with a diffuse left-sided facial swelling and dull pain that gradually developed over 8 months, presented to us with misdiagnosis and poor management. Examination was found to have a firm swelling involving the buccal region, and left posterior mandible with intact overlying skin and mucosa, and palpable cervical lymphadenopathy. Imaging showed a heterogeneous osteolytic lesion of left ramus extending to the surrounding soft tissue. The diagnosis with oro-facial tuberculosis was established by histopathological study and confirmed by the Mantoux test and polymerase chain reaction. Although it occurs rarely, oro-facial tuberculosis has detrimental local and systemic effects, and devoid of characteristic clinical and radiographic features, poses a diagnostic challenge.http://www.sciencedirect.com/science/article/pii/S2214250920301335OsteomyelitisTuberculosisOro-facial tuberculosisMandibular osteomyelitisCervicofacial infectionIraq
spellingShingle Sabah Abdulaziz Issa
Hussein Ali Abdulnabi
Mustafa Emaduldeen Jameel
Orofacial tuberculosis: A diagnostic challenge
IDCases
Osteomyelitis
Tuberculosis
Oro-facial tuberculosis
Mandibular osteomyelitis
Cervicofacial infection
Iraq
title Orofacial tuberculosis: A diagnostic challenge
title_full Orofacial tuberculosis: A diagnostic challenge
title_fullStr Orofacial tuberculosis: A diagnostic challenge
title_full_unstemmed Orofacial tuberculosis: A diagnostic challenge
title_short Orofacial tuberculosis: A diagnostic challenge
title_sort orofacial tuberculosis a diagnostic challenge
topic Osteomyelitis
Tuberculosis
Oro-facial tuberculosis
Mandibular osteomyelitis
Cervicofacial infection
Iraq
url http://www.sciencedirect.com/science/article/pii/S2214250920301335
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AT husseinaliabdulnabi orofacialtuberculosisadiagnosticchallenge
AT mustafaemaduldeenjameel orofacialtuberculosisadiagnosticchallenge