Research progress on pH-sensitive drug delivery systems in the treatment of head and neck squamous cell carcinoma

Research progress on pH-sensitive drug delivery systems in the treatment of head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is a common tumor type. At present, surgical treatment, radiotherapy and chemotherapy are the main treatments for HNSCC, but these treatments have not achieved satisfactory results. The pH-sensitive drug delivery system is an environmental stimuli-respon...

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Bibliographic Details
Main Authors: HE Hongzhi, CHENG Lei, LI Bolei
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2022-10-01
Series:口腔疾病防治
Subjects:
ph sensitivity
drug delivery system
targeted therapy
controlled drug release
head and neck squamous cell carcinoma
oral squamous cell carcinoma
tumor microenvironment
chemotherapy
drug resistance
protonated group
acid-labile chemical bond
Online Access:http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2022.10.010

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