Superficial shaving combined with photodynamic therapy is effective as a treatment for condyloma acuminatum
Abstract Condyloma acuminatum is a common sexually transmitted disease caused by human papillomavirus. Its prevalence and recurrence rates are high. While there are multiple treatment options for condyloma acuminatum, no single therapy form is effective in achieving complete remission. Photodynamic...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2023-03-01
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| Series: | Translational Biophotonics |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/tbio.202200007 |
| _version_ | 1797840505152733184 |
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| author | Jie Pan Mingliang Chen Shuang Zhao Juan Su |
| author_facet | Jie Pan Mingliang Chen Shuang Zhao Juan Su |
| author_sort | Jie Pan |
| collection | DOAJ |
| description | Abstract Condyloma acuminatum is a common sexually transmitted disease caused by human papillomavirus. Its prevalence and recurrence rates are high. While there are multiple treatment options for condyloma acuminatum, no single therapy form is effective in achieving complete remission. Photodynamic therapy (PDT) was shown to be very promising as a treatment option for condyloma acuminatum. However, for some patients the therapeutic result after a single PDT session is not satisfactory. Thus, it is necessary to develop an effective treatment method for recalcitrant condyloma acuminatum. We hypothesize that suboptimal therapeutic results after a single PDT may be caused by an insufficient penetration of the photosensitizer into the tissue. Here, we applied a combination of superficial shaving and PDT to address this issue. All patients were satisfied with the effect of the treatment, and their quality of life improved significantly. Pain was the major adverse event during treatment but was acceptable to all patients. Therefore, superficial shaving in combination with PDT is safe and effective. |
| first_indexed | 2024-04-09T16:16:26Z |
| format | Article |
| id | doaj.art-d594a06e9112472c93339a41dcbfa422 |
| institution | Directory Open Access Journal |
| issn | 2627-1850 |
| language | English |
| last_indexed | 2024-04-09T16:16:26Z |
| publishDate | 2023-03-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Translational Biophotonics |
| spelling | doaj.art-d594a06e9112472c93339a41dcbfa4222023-04-24T05:21:43ZengWiley-VCHTranslational Biophotonics2627-18502023-03-0151n/an/a10.1002/tbio.202200007Superficial shaving combined with photodynamic therapy is effective as a treatment for condyloma acuminatumJie Pan0Mingliang Chen1Shuang Zhao2Juan Su3Department of Dermatology, Xiangya Hospital Central South University Changsha ChinaDepartment of Dermatology, Xiangya Hospital Central South University Changsha ChinaDepartment of Dermatology, Xiangya Hospital Central South University Changsha ChinaDepartment of Dermatology, Xiangya Hospital Central South University Changsha ChinaAbstract Condyloma acuminatum is a common sexually transmitted disease caused by human papillomavirus. Its prevalence and recurrence rates are high. While there are multiple treatment options for condyloma acuminatum, no single therapy form is effective in achieving complete remission. Photodynamic therapy (PDT) was shown to be very promising as a treatment option for condyloma acuminatum. However, for some patients the therapeutic result after a single PDT session is not satisfactory. Thus, it is necessary to develop an effective treatment method for recalcitrant condyloma acuminatum. We hypothesize that suboptimal therapeutic results after a single PDT may be caused by an insufficient penetration of the photosensitizer into the tissue. Here, we applied a combination of superficial shaving and PDT to address this issue. All patients were satisfied with the effect of the treatment, and their quality of life improved significantly. Pain was the major adverse event during treatment but was acceptable to all patients. Therefore, superficial shaving in combination with PDT is safe and effective.https://doi.org/10.1002/tbio.202200007condyloma acuminatumphotodynamic therapyrecalcitrant condyloma acuminatumsuperficial shaving |
| spellingShingle | Jie Pan Mingliang Chen Shuang Zhao Juan Su Superficial shaving combined with photodynamic therapy is effective as a treatment for condyloma acuminatum Translational Biophotonics condyloma acuminatum photodynamic therapy recalcitrant condyloma acuminatum superficial shaving |
| title | Superficial shaving combined with photodynamic therapy is effective as a treatment for condyloma acuminatum |
| title_full | Superficial shaving combined with photodynamic therapy is effective as a treatment for condyloma acuminatum |
| title_fullStr | Superficial shaving combined with photodynamic therapy is effective as a treatment for condyloma acuminatum |
| title_full_unstemmed | Superficial shaving combined with photodynamic therapy is effective as a treatment for condyloma acuminatum |
| title_short | Superficial shaving combined with photodynamic therapy is effective as a treatment for condyloma acuminatum |
| title_sort | superficial shaving combined with photodynamic therapy is effective as a treatment for condyloma acuminatum |
| topic | condyloma acuminatum photodynamic therapy recalcitrant condyloma acuminatum superficial shaving |
| url | https://doi.org/10.1002/tbio.202200007 |
| work_keys_str_mv | AT jiepan superficialshavingcombinedwithphotodynamictherapyiseffectiveasatreatmentforcondylomaacuminatum AT mingliangchen superficialshavingcombinedwithphotodynamictherapyiseffectiveasatreatmentforcondylomaacuminatum AT shuangzhao superficialshavingcombinedwithphotodynamictherapyiseffectiveasatreatmentforcondylomaacuminatum AT juansu superficialshavingcombinedwithphotodynamictherapyiseffectiveasatreatmentforcondylomaacuminatum |