Trichosanthis Semen and Zingiberis Rhizoma Mixture Ameliorates Lipopolysaccharide-Induced Memory Dysfunction by Inhibiting Neuroinflammation
Neuroinflammation, a key pathological contributor to various neurodegenerative diseases, is mediated by microglial activation and subsequent secretion of inflammatory cytokines via the mitogen-activated protein kinase (MAPK) signaling pathway. Moreover, neuroinflammation leads to synaptic loss and m...
Main Authors: | Hyeri Im, In Gyoung Ju, Jin Hee Kim, Seungmin Lee, Myung Sook Oh |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/22/14015 |
Similar Items
-
Foeniculum vulgare Mill. inhibits lipopolysaccharide-induced microglia activation and ameliorates neuroinflammation-mediated behavioral deficits in mice
by: Sushruta Koppula, et al.
Published: (2024-01-01) -
Trichosanthis Semen Suppresses Lipopolysaccharide-Induced Neuroinflammation by Regulating the NF-κB Signaling Pathway and HO-1 Expression in Microglia
by: Seungmin Lee, et al.
Published: (2021-12-01) -
Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation
by: Fan Kai, et al.
Published: (2012-05-01) -
Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures
by: Bei Zhang, et al.
Published: (2019-01-01) -
Mild endoplasmic reticulum stress ameliorates lipopolysaccharide-induced neuroinflammation and cognitive impairment via regulation of microglial polarization
by: Yi-wei Wang, et al.
Published: (2017-11-01)