LncRNA WDFY3-AS2 promotes cisplatin resistance and the cancer stem cell in ovarian cancer by regulating hsa-miR-139-5p/SDC4 axis

LncRNA WDFY3-AS2 promotes cisplatin resistance and the cancer stem cell in ovarian cancer by regulating hsa-miR-139-5p/SDC4 axis

Abstract Background Ovarian cancer (OC) is a high-mortality gynecological cancer that is typically treated with cisplatin, although such treatment often results in chemoresistance. Ovarian cancer resistance is usually related to cell stemness. Herein, we explored the function of lncRNA WDFY3-AS2 in...

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Bibliographic Details
Main Authors: Yue Wu, Ting Wang, Lin Xia, Mei Zhang
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cancer Cell International
Subjects:
lncRNA WDFY3-AS2
Hsa-miR-139-5p
SDC4
Cisplatin resistance
Cancer stem cells
Ovarian cancer
Online Access:https://doi.org/10.1186/s12935-021-01993-x

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