The Role of Advanced Glycation End Products in Diabetic Vascular Complications
In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complicatio...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Korean Diabetes Association
2018-05-01
|
| Series: | Diabetes & Metabolism Journal |
| Subjects: | |
| Online Access: | https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-42-188.pdf |
| _version_ | 1818597261014204416 |
|---|---|
| author | Sang Youl Rhee Young Seol Kim |
| author_facet | Sang Youl Rhee Young Seol Kim |
| author_sort | Sang Youl Rhee |
| collection | DOAJ |
| description | In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various mechanisms. Active interventions for glucose and related risk factors may help improve the clinical course of patients by reducing AGEs. This review summarizes recent updates on AGEs that have a significant impact on diabetic vascular complications. |
| first_indexed | 2024-12-16T11:44:59Z |
| format | Article |
| id | doaj.art-d59984f065734c6cb993309bd8dcf86c |
| institution | Directory Open Access Journal |
| issn | 2233-6079 2233-6087 |
| language | English |
| last_indexed | 2024-12-16T11:44:59Z |
| publishDate | 2018-05-01 |
| publisher | Korean Diabetes Association |
| record_format | Article |
| series | Diabetes & Metabolism Journal |
| spelling | doaj.art-d59984f065734c6cb993309bd8dcf86c2022-12-21T22:32:51ZengKorean Diabetes AssociationDiabetes & Metabolism Journal2233-60792233-60872018-05-0142318819510.4093/dmj.2017.0105The Role of Advanced Glycation End Products in Diabetic Vascular ComplicationsSang Youl RheeYoung Seol KimIn cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs, and they play an important role in the development of diabetic vascular complications through various mechanisms. Active interventions for glucose and related risk factors may help improve the clinical course of patients by reducing AGEs. This review summarizes recent updates on AGEs that have a significant impact on diabetic vascular complications.https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-42-188.pdfDiabetes complicationsGlycation end products, advancedReceptor for advanced glycation end products |
| spellingShingle | Sang Youl Rhee Young Seol Kim The Role of Advanced Glycation End Products in Diabetic Vascular Complications Diabetes & Metabolism Journal Diabetes complications Glycation end products, advanced Receptor for advanced glycation end products |
| title | The Role of Advanced Glycation End Products in Diabetic Vascular Complications |
| title_full | The Role of Advanced Glycation End Products in Diabetic Vascular Complications |
| title_fullStr | The Role of Advanced Glycation End Products in Diabetic Vascular Complications |
| title_full_unstemmed | The Role of Advanced Glycation End Products in Diabetic Vascular Complications |
| title_short | The Role of Advanced Glycation End Products in Diabetic Vascular Complications |
| title_sort | role of advanced glycation end products in diabetic vascular complications |
| topic | Diabetes complications Glycation end products, advanced Receptor for advanced glycation end products |
| url | https://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-42-188.pdf |
| work_keys_str_mv | AT sangyoulrhee theroleofadvancedglycationendproductsindiabeticvascularcomplications AT youngseolkim theroleofadvancedglycationendproductsindiabeticvascularcomplications AT sangyoulrhee roleofadvancedglycationendproductsindiabeticvascularcomplications AT youngseolkim roleofadvancedglycationendproductsindiabeticvascularcomplications |