Suicide Attempts, Neurocognitive Dysfunctions and Clinical Correlates in Middle-Aged and Elderly Chinese Schizophrenia Patients
Background: Suicide is a common and complex symptom of schizophrenia that may be related to clinical variables and neurocognitive function. This study aimed to investigate the associated correlates of suicide attempts in Chinese middle-aged and elderly inpatients with schizophrenia, including demogr...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-05-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2021.684653/full |
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| author | Yuanyuan Huang Kai Wu Rui Jiang Xiaoying Zeng Xiaoying Zeng Sumiao Zhou Weijian Guo Yangdong Feng Caimei Zou Hehua Li Ting Li Yuping Ning Yuping Ning Yuping Ning Mingzhe Yang Fengchun Wu Fengchun Wu Fengchun Wu |
| author_facet | Yuanyuan Huang Kai Wu Rui Jiang Xiaoying Zeng Xiaoying Zeng Sumiao Zhou Weijian Guo Yangdong Feng Caimei Zou Hehua Li Ting Li Yuping Ning Yuping Ning Yuping Ning Mingzhe Yang Fengchun Wu Fengchun Wu Fengchun Wu |
| author_sort | Yuanyuan Huang |
| collection | DOAJ |
| description | Background: Suicide is a common and complex symptom of schizophrenia that may be related to clinical variables and neurocognitive function. This study aimed to investigate the associated correlates of suicide attempts in Chinese middle-aged and elderly inpatients with schizophrenia, including demographic and clinical characteristics and cognitive level, which has not yet been reported.Methods: A total of 426 schizophrenia inpatients were recruited for this study. Clinical symptoms were evaluated using the Positive and Negative Syndrome Scale (PANSS). Neurocognitive function was measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).Results: The prevalence of suicide attempts in middle-aged and elderly Chinese schizophrenia patients was 13.3%. Female patients had a higher suicide rate than male patients. Patients with suicide attempts had significantly higher PANSS-positive subscores, depressive subscores, and RBANS-story recall than non-attempter patients (all p < 0.05). Multiple logistic regression showed that gender, positive subscore, depressive subscore and RBANS-story recall (OR = 1.10–2.19, p < 0.05) were independently associated with suicide attempts in middle-aged and elderly schizophrenia patients.Conclusions: Our study showed that the rate of suicide attempts in Chinese middle-aged and elderly schizophrenia patients is high. Compared to non-attempters, there are less cognitive impairments, more clinical symptoms, and more female patients in the suicide attempters. |
| first_indexed | 2024-12-16T23:21:26Z |
| format | Article |
| id | doaj.art-d599f9cf8edf428ca03cf3812a8fc9a3 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-16T23:21:26Z |
| publishDate | 2021-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-d599f9cf8edf428ca03cf3812a8fc9a32022-12-21T22:12:09ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402021-05-011210.3389/fpsyt.2021.684653684653Suicide Attempts, Neurocognitive Dysfunctions and Clinical Correlates in Middle-Aged and Elderly Chinese Schizophrenia PatientsYuanyuan Huang0Kai Wu1Rui Jiang2Xiaoying Zeng3Xiaoying Zeng4Sumiao Zhou5Weijian Guo6Yangdong Feng7Caimei Zou8Hehua Li9Ting Li10Yuping Ning11Yuping Ning12Yuping Ning13Mingzhe Yang14Fengchun Wu15Fengchun Wu16Fengchun Wu17Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Biomedical Engineering, School of Materials Science and Engineering, South China University of Technology (SCUT), Guangzhou, ChinaQingdao Mental Health Center, Qingdao University, Qingdao, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaNew Growth of Guangzhou, Guangzhou, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaThe First School of Clinical Medicine, Southern Medical University, Guangzhou, ChinaGuangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaDepartment of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou, ChinaThe First School of Clinical Medicine, Southern Medical University, Guangzhou, ChinaGuangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, ChinaBackground: Suicide is a common and complex symptom of schizophrenia that may be related to clinical variables and neurocognitive function. This study aimed to investigate the associated correlates of suicide attempts in Chinese middle-aged and elderly inpatients with schizophrenia, including demographic and clinical characteristics and cognitive level, which has not yet been reported.Methods: A total of 426 schizophrenia inpatients were recruited for this study. Clinical symptoms were evaluated using the Positive and Negative Syndrome Scale (PANSS). Neurocognitive function was measured by the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS).Results: The prevalence of suicide attempts in middle-aged and elderly Chinese schizophrenia patients was 13.3%. Female patients had a higher suicide rate than male patients. Patients with suicide attempts had significantly higher PANSS-positive subscores, depressive subscores, and RBANS-story recall than non-attempter patients (all p < 0.05). Multiple logistic regression showed that gender, positive subscore, depressive subscore and RBANS-story recall (OR = 1.10–2.19, p < 0.05) were independently associated with suicide attempts in middle-aged and elderly schizophrenia patients.Conclusions: Our study showed that the rate of suicide attempts in Chinese middle-aged and elderly schizophrenia patients is high. Compared to non-attempters, there are less cognitive impairments, more clinical symptoms, and more female patients in the suicide attempters.https://www.frontiersin.org/articles/10.3389/fpsyt.2021.684653/fullsuicide attemptsneurocognitive functionschizophreniaPANSSmiddle-aged and elderly |
| spellingShingle | Yuanyuan Huang Kai Wu Rui Jiang Xiaoying Zeng Xiaoying Zeng Sumiao Zhou Weijian Guo Yangdong Feng Caimei Zou Hehua Li Ting Li Yuping Ning Yuping Ning Yuping Ning Mingzhe Yang Fengchun Wu Fengchun Wu Fengchun Wu Suicide Attempts, Neurocognitive Dysfunctions and Clinical Correlates in Middle-Aged and Elderly Chinese Schizophrenia Patients Frontiers in Psychiatry suicide attempts neurocognitive function schizophrenia PANSS middle-aged and elderly |
| title | Suicide Attempts, Neurocognitive Dysfunctions and Clinical Correlates in Middle-Aged and Elderly Chinese Schizophrenia Patients |
| title_full | Suicide Attempts, Neurocognitive Dysfunctions and Clinical Correlates in Middle-Aged and Elderly Chinese Schizophrenia Patients |
| title_fullStr | Suicide Attempts, Neurocognitive Dysfunctions and Clinical Correlates in Middle-Aged and Elderly Chinese Schizophrenia Patients |
| title_full_unstemmed | Suicide Attempts, Neurocognitive Dysfunctions and Clinical Correlates in Middle-Aged and Elderly Chinese Schizophrenia Patients |
| title_short | Suicide Attempts, Neurocognitive Dysfunctions and Clinical Correlates in Middle-Aged and Elderly Chinese Schizophrenia Patients |
| title_sort | suicide attempts neurocognitive dysfunctions and clinical correlates in middle aged and elderly chinese schizophrenia patients |
| topic | suicide attempts neurocognitive function schizophrenia PANSS middle-aged and elderly |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2021.684653/full |
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