Real-time precision opto-control of chemical processes in live cells
There is a need to control molecular activities at high spatial precision. Here the authors report a real-time precision opto-control technology that detects a chemical-specific optical response from molecular targets, and precisely control photoswitchable microtubule polymerization inhibitors in ce...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-32071-z |
| _version_ | 1811223025125687296 |
|---|---|
| author | Matthew G. Clark Gil A. Gonzalez Yiyang Luo Jesus A. Aldana-Mendoza Mark S. Carlsen Gregory Eakins Mingji Dai Chi Zhang |
| author_facet | Matthew G. Clark Gil A. Gonzalez Yiyang Luo Jesus A. Aldana-Mendoza Mark S. Carlsen Gregory Eakins Mingji Dai Chi Zhang |
| author_sort | Matthew G. Clark |
| collection | DOAJ |
| description | There is a need to control molecular activities at high spatial precision. Here the authors report a real-time precision opto-control technology that detects a chemical-specific optical response from molecular targets, and precisely control photoswitchable microtubule polymerization inhibitors in cells. |
| first_indexed | 2024-04-12T08:25:50Z |
| format | Article |
| id | doaj.art-d59b59a2f8e94c37b06817a6ddd06a58 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-12T08:25:50Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-d59b59a2f8e94c37b06817a6ddd06a582022-12-22T03:40:24ZengNature PortfolioNature Communications2041-17232022-07-0113111210.1038/s41467-022-32071-zReal-time precision opto-control of chemical processes in live cellsMatthew G. Clark0Gil A. Gonzalez1Yiyang Luo2Jesus A. Aldana-Mendoza3Mark S. Carlsen4Gregory Eakins5Mingji Dai6Chi Zhang7Department of Chemistry, Purdue UniversityDepartment of Chemistry, Purdue UniversityDepartment of Chemistry, Purdue UniversityDepartment of Chemistry, Purdue UniversityDepartment of Chemistry, Purdue UniversityDepartment of Chemistry, Purdue UniversityDepartment of Chemistry, Purdue UniversityDepartment of Chemistry, Purdue UniversityThere is a need to control molecular activities at high spatial precision. Here the authors report a real-time precision opto-control technology that detects a chemical-specific optical response from molecular targets, and precisely control photoswitchable microtubule polymerization inhibitors in cells.https://doi.org/10.1038/s41467-022-32071-z |
| spellingShingle | Matthew G. Clark Gil A. Gonzalez Yiyang Luo Jesus A. Aldana-Mendoza Mark S. Carlsen Gregory Eakins Mingji Dai Chi Zhang Real-time precision opto-control of chemical processes in live cells Nature Communications |
| title | Real-time precision opto-control of chemical processes in live cells |
| title_full | Real-time precision opto-control of chemical processes in live cells |
| title_fullStr | Real-time precision opto-control of chemical processes in live cells |
| title_full_unstemmed | Real-time precision opto-control of chemical processes in live cells |
| title_short | Real-time precision opto-control of chemical processes in live cells |
| title_sort | real time precision opto control of chemical processes in live cells |
| url | https://doi.org/10.1038/s41467-022-32071-z |
| work_keys_str_mv | AT matthewgclark realtimeprecisionoptocontrolofchemicalprocessesinlivecells AT gilagonzalez realtimeprecisionoptocontrolofchemicalprocessesinlivecells AT yiyangluo realtimeprecisionoptocontrolofchemicalprocessesinlivecells AT jesusaaldanamendoza realtimeprecisionoptocontrolofchemicalprocessesinlivecells AT markscarlsen realtimeprecisionoptocontrolofchemicalprocessesinlivecells AT gregoryeakins realtimeprecisionoptocontrolofchemicalprocessesinlivecells AT mingjidai realtimeprecisionoptocontrolofchemicalprocessesinlivecells AT chizhang realtimeprecisionoptocontrolofchemicalprocessesinlivecells |