Making the Case for Standardized Outcome Measures in Exercise and Physical Activity Research in Chronic Kidney Disease

Physical activity and exercise are core components of lifestyle modification strategies for the management of chronic kidney disease (CKD). Yet, physical activity levels have consistently remained poor across all stages of CKD. Exercise interventions, including aerobic and resistance training, and l...

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Main Authors: Thomas J. Wilkinson, Jennifer M. MacRae, Stephanie Thompson, Clara Bohm
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Kidney and Dialysis
Subjects:
Online Access:https://www.mdpi.com/2673-8236/3/2/20
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author Thomas J. Wilkinson
Jennifer M. MacRae
Stephanie Thompson
Clara Bohm
author_facet Thomas J. Wilkinson
Jennifer M. MacRae
Stephanie Thompson
Clara Bohm
author_sort Thomas J. Wilkinson
collection DOAJ
description Physical activity and exercise are core components of lifestyle modification strategies for the management of chronic kidney disease (CKD). Yet, physical activity levels have consistently remained poor across all stages of CKD. Exercise interventions, including aerobic and resistance training, and lifestyle interventions promoting physical activity, have been shown to improve a multitude of clinical endpoints and factors important to patients; however, despite the evidence, the provision of physical activity in clinical practice is still inadequate. The usefulness of any study hinges on the adequacy and clinical relevance of the outcomes and outcome measures used. Inconsistent reporting and wide disparities in outcome use across studies limit evidence synthesis to help guide clinical practice. The kidney exercise and physical activity field has been particularly prone to inconsistent outcome reporting. To ensure research is relevant and able to influence clinical practice and future research, we need to ensure the use (and reporting) of standardized, relevant outcome measures. Core outcome sets (COS) have been widely developed across many chronic conditions, yet these COS have not been tailored to physical activity and exercise in CKD. Outcomes in clinical research need to be relevant to the intervention being employed. From this perspective, we summarize the importance that standardizing outcomes and outcome measures may have in relation to physical activity and exercise interventions for people living with kidney disease.
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spelling doaj.art-d59e6add73214a11bec92e88a8bd01732023-11-18T11:12:48ZengMDPI AGKidney and Dialysis2673-82362023-05-013221922810.3390/kidneydial3020020Making the Case for Standardized Outcome Measures in Exercise and Physical Activity Research in Chronic Kidney DiseaseThomas J. Wilkinson0Jennifer M. MacRae1Stephanie Thompson2Clara Bohm3Leicester Diabetes Centre, University of Leicester, Leicester LE5 4PW, UKCumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, CanadaDepartment of Medicine, University of Alberta, Edmonton, AB T6G 2R3, CanadaDepartment of Internal Medicine, University of Manitoba, Winnipeg, MB R3T 2N2, CanadaPhysical activity and exercise are core components of lifestyle modification strategies for the management of chronic kidney disease (CKD). Yet, physical activity levels have consistently remained poor across all stages of CKD. Exercise interventions, including aerobic and resistance training, and lifestyle interventions promoting physical activity, have been shown to improve a multitude of clinical endpoints and factors important to patients; however, despite the evidence, the provision of physical activity in clinical practice is still inadequate. The usefulness of any study hinges on the adequacy and clinical relevance of the outcomes and outcome measures used. Inconsistent reporting and wide disparities in outcome use across studies limit evidence synthesis to help guide clinical practice. The kidney exercise and physical activity field has been particularly prone to inconsistent outcome reporting. To ensure research is relevant and able to influence clinical practice and future research, we need to ensure the use (and reporting) of standardized, relevant outcome measures. Core outcome sets (COS) have been widely developed across many chronic conditions, yet these COS have not been tailored to physical activity and exercise in CKD. Outcomes in clinical research need to be relevant to the intervention being employed. From this perspective, we summarize the importance that standardizing outcomes and outcome measures may have in relation to physical activity and exercise interventions for people living with kidney disease.https://www.mdpi.com/2673-8236/3/2/20outcomesoutcome measurescore outcome measure setexercisephysical activity
spellingShingle Thomas J. Wilkinson
Jennifer M. MacRae
Stephanie Thompson
Clara Bohm
Making the Case for Standardized Outcome Measures in Exercise and Physical Activity Research in Chronic Kidney Disease
Kidney and Dialysis
outcomes
outcome measures
core outcome measure set
exercise
physical activity
title Making the Case for Standardized Outcome Measures in Exercise and Physical Activity Research in Chronic Kidney Disease
title_full Making the Case for Standardized Outcome Measures in Exercise and Physical Activity Research in Chronic Kidney Disease
title_fullStr Making the Case for Standardized Outcome Measures in Exercise and Physical Activity Research in Chronic Kidney Disease
title_full_unstemmed Making the Case for Standardized Outcome Measures in Exercise and Physical Activity Research in Chronic Kidney Disease
title_short Making the Case for Standardized Outcome Measures in Exercise and Physical Activity Research in Chronic Kidney Disease
title_sort making the case for standardized outcome measures in exercise and physical activity research in chronic kidney disease
topic outcomes
outcome measures
core outcome measure set
exercise
physical activity
url https://www.mdpi.com/2673-8236/3/2/20
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