Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young adults

Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young adults

Background: The hypothalamus plays a crucial role in regulating sleep-wake cycle and motivated behavior. Sleep disturbance is associated with impairment in cognitive and affective functions. However, how hypothalamic dysfunction may contribute to inter-related sleep, cognitive, and emotional deficit...

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Bibliographic Details
Main Authors: Guangfei Li, Yu Chen, Shefali Chaudhary, Clara S Li, Dongmei Hao, Lin Yang, Chiang-Shan R. Li
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:NeuroImage
Subjects:
PSQI
Anxiety
rsFC
Hypothalamus
fMRI
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811923004913

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