Neurological Manifestations in Familial Mediterranean Fever
Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by mutations of the MEFV gene. The main clinical manifestations are recurrent fever and serous inflammation in various parts of the body. Some patients with FMF may also develop neurological manifestations such as epilepsy, dem...
| Main Authors: | , |
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| Format: | Article |
| Language: | zho |
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Editorial Office of Medical Journal of Peking Union Medical College Hospital
2023-03-01
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| Series: | Xiehe Yixue Zazhi |
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| Online Access: | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0093 |
| _version_ | 1797851469684146176 |
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| author | DONG Yaohua SONG Hongmei |
| author_facet | DONG Yaohua SONG Hongmei |
| author_sort | DONG Yaohua |
| collection | DOAJ |
| description | Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by mutations of the MEFV gene. The main clinical manifestations are recurrent fever and serous inflammation in various parts of the body. Some patients with FMF may also develop neurological manifestations such as epilepsy, demyelinating disease, aseptic meningitis. As neurological manifestations are rare in patients with FMF, the association between the two is often overlooked in clinical practice. In this paper, we reviewed the neurological manifestations of FMF and their relationship with genotypes, so as to deepen the understanding of the clinical manifestations of FMF and provide help for the diagnosis and treatment of patients with neurological manifestations. |
| first_indexed | 2024-04-09T19:17:17Z |
| format | Article |
| id | doaj.art-d5a0947ab5cf4aff86deeddeeb7c5885 |
| institution | Directory Open Access Journal |
| issn | 1674-9081 |
| language | zho |
| last_indexed | 2024-04-09T19:17:17Z |
| publishDate | 2023-03-01 |
| publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
| record_format | Article |
| series | Xiehe Yixue Zazhi |
| spelling | doaj.art-d5a0947ab5cf4aff86deeddeeb7c58852023-04-06T02:17:32ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812023-03-0114233433810.12290/xhyxzz.2022-0093Neurological Manifestations in Familial Mediterranean FeverDONG YaohuaSONG HongmeiFamilial Mediterranean fever (FMF) is an autoinflammatory disease caused by mutations of the MEFV gene. The main clinical manifestations are recurrent fever and serous inflammation in various parts of the body. Some patients with FMF may also develop neurological manifestations such as epilepsy, demyelinating disease, aseptic meningitis. As neurological manifestations are rare in patients with FMF, the association between the two is often overlooked in clinical practice. In this paper, we reviewed the neurological manifestations of FMF and their relationship with genotypes, so as to deepen the understanding of the clinical manifestations of FMF and provide help for the diagnosis and treatment of patients with neurological manifestations.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0093familial mediterranean feverneurological manifestationsgenotype |
| spellingShingle | DONG Yaohua SONG Hongmei Neurological Manifestations in Familial Mediterranean Fever Xiehe Yixue Zazhi familial mediterranean fever neurological manifestations genotype |
| title | Neurological Manifestations in Familial Mediterranean Fever |
| title_full | Neurological Manifestations in Familial Mediterranean Fever |
| title_fullStr | Neurological Manifestations in Familial Mediterranean Fever |
| title_full_unstemmed | Neurological Manifestations in Familial Mediterranean Fever |
| title_short | Neurological Manifestations in Familial Mediterranean Fever |
| title_sort | neurological manifestations in familial mediterranean fever |
| topic | familial mediterranean fever neurological manifestations genotype |
| url | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2022-0093 |
| work_keys_str_mv | AT dongyaohua neurologicalmanifestationsinfamilialmediterraneanfever AT songhongmei neurologicalmanifestationsinfamilialmediterraneanfever |