LRRTM2 controls presynapse nano-organization and AMPA receptor sub-positioning through Neurexin-binding interface

Abstract Synapses are organized into nanocolumns that control synaptic transmission efficacy through precise alignment of postsynaptic neurotransmitter receptors and presynaptic release sites. Recent evidence show that Leucine-Rich Repeat Transmembrane protein LRRTM2, highly enriched and confined at...

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Hlavní autoři: Konstantina Liouta, Malgorzata Lubas, Vasika Venugopal, Julia Chabbert, Caroline Jeannière, Candice Diaz, Matthieu Munier, Béatrice Tessier, Stéphane Claverol, Alexandre Favereaux, Matthieu Sainlos, Joris de Wit, Mathieu Letellier, Olivier Thoumine, Ingrid Chamma
Médium: Článek
Jazyk:English
Vydáno: Nature Portfolio 2024-10-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-024-53090-y