Classical and Atypical Scrapie in Sheep and Goats. Review on the Etiology, Genetic Factors, Pathogenesis, Diagnosis, and Control Measures of Both Diseases

Classical and Atypical Scrapie in Sheep and Goats. Review on the Etiology, Genetic Factors, Pathogenesis, Diagnosis, and Control Measures of Both Diseases

Prion diseases, such as scrapie, are neurodegenerative diseases with a fatal outcome, caused by a conformational change of the cellular prion protein (PrP<sup>C</sup>), originating with the pathogenic form (PrP<sup>Sc</sup>). Classical scrapie in small ruminants is the paradi...

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Bibliographic Details
Main Authors: Cristina Acín, Rosa Bolea, Marta Monzón, Eva Monleón, Bernardino Moreno, Hicham Filali, Belén Marín, Diego Sola, Marina Betancor, Isabel M. Guijarro, Mirta García, Antonia Vargas, Juan José Badiola
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Animals
Subjects:
classical scrapie
atypical scrapie
prion disease
sheep
goat
review
Online Access:https://www.mdpi.com/2076-2615/11/3/691

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