Inversely Finding Peculiar Reaction Conditions toward Microfluidic Droplet Synthesis

With the development of microfluidics, there are increasing reports of syntheses using not only conventional laminar flow at the microscale, but also the dissociation and aggregation of microdroplets. It is known, to some extent, that the microfluidics scale differs from normal scales in terms of th...

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Main Author: Takashiro Akitsu
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Reactions
Subjects:
Online Access:https://www.mdpi.com/2624-781X/4/4/36
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author Takashiro Akitsu
author_facet Takashiro Akitsu
author_sort Takashiro Akitsu
collection DOAJ
description With the development of microfluidics, there are increasing reports of syntheses using not only conventional laminar flow at the microscale, but also the dissociation and aggregation of microdroplets. It is known, to some extent, that the microfluidics scale differs from normal scales in terms of the specific surface area, mass diffusion, and heat conduction; these are opposite to those in scale-up in-plant chemical engineering. However, it is not easy to determine what changes when the microdroplet flows through the channel. In this context, the author would like to clarify how the behavior of chemical species, which is expected to appear unique at the nanoscale, contributes to chemical reactions. What do we need in order to develop a completely new theory of chemical reactions? The characteristics of chemical reactions on the nanoscale are clarified via the encountering of solutions by the microfluidic device itself, or the chemical reaction of nanoscale droplets generated by the microfluidic device. Specifically, in recent years, experimental reports have accumulated that are expected to develop a fluidic device that can stably generate nanodroplets, and complex reactions of different reactivity are expected to occur that are specific to the nanoscale. In this short article, microfluidic devices, nanoscale droplets, experimental synthetic examples, and findings that may provide solutions are described.
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spelling doaj.art-d5a6d7af10334f81a7d6170da56148ab2023-12-22T14:38:14ZengMDPI AGReactions2624-781X2023-10-014464765610.3390/reactions4040036Inversely Finding Peculiar Reaction Conditions toward Microfluidic Droplet SynthesisTakashiro Akitsu0Department of Chemistry, Faculty of Science, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, JapanWith the development of microfluidics, there are increasing reports of syntheses using not only conventional laminar flow at the microscale, but also the dissociation and aggregation of microdroplets. It is known, to some extent, that the microfluidics scale differs from normal scales in terms of the specific surface area, mass diffusion, and heat conduction; these are opposite to those in scale-up in-plant chemical engineering. However, it is not easy to determine what changes when the microdroplet flows through the channel. In this context, the author would like to clarify how the behavior of chemical species, which is expected to appear unique at the nanoscale, contributes to chemical reactions. What do we need in order to develop a completely new theory of chemical reactions? The characteristics of chemical reactions on the nanoscale are clarified via the encountering of solutions by the microfluidic device itself, or the chemical reaction of nanoscale droplets generated by the microfluidic device. Specifically, in recent years, experimental reports have accumulated that are expected to develop a fluidic device that can stably generate nanodroplets, and complex reactions of different reactivity are expected to occur that are specific to the nanoscale. In this short article, microfluidic devices, nanoscale droplets, experimental synthetic examples, and findings that may provide solutions are described.https://www.mdpi.com/2624-781X/4/4/36microfluidicsmicrodropletmetal complexespreparationreaction condition
spellingShingle Takashiro Akitsu
Inversely Finding Peculiar Reaction Conditions toward Microfluidic Droplet Synthesis
Reactions
microfluidics
microdroplet
metal complexes
preparation
reaction condition
title Inversely Finding Peculiar Reaction Conditions toward Microfluidic Droplet Synthesis
title_full Inversely Finding Peculiar Reaction Conditions toward Microfluidic Droplet Synthesis
title_fullStr Inversely Finding Peculiar Reaction Conditions toward Microfluidic Droplet Synthesis
title_full_unstemmed Inversely Finding Peculiar Reaction Conditions toward Microfluidic Droplet Synthesis
title_short Inversely Finding Peculiar Reaction Conditions toward Microfluidic Droplet Synthesis
title_sort inversely finding peculiar reaction conditions toward microfluidic droplet synthesis
topic microfluidics
microdroplet
metal complexes
preparation
reaction condition
url https://www.mdpi.com/2624-781X/4/4/36
work_keys_str_mv AT takashiroakitsu inverselyfindingpeculiarreactionconditionstowardmicrofluidicdropletsynthesis