Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case Report

A male patient had suffered miscellaneous ocular symptoms for 20 years with auricular dysmorphosis and was diagnosed with Relapsing Polychondritis (RP) in the ear, nose, joints, and costal cartilage. The patient lost his vision owing to recurrent ocular symptoms for decades. He presented an increase...

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Main Authors: Yu Zhang, Li Zhang, Zhen Wu, Jianping Tang, Xuan Wang
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2022-03-01
Series:Iranian Journal of Immunology
Subjects:
Online Access:https://iji.sums.ac.ir/article_48268_61e2d713bb7e2654e02cdc584966021f.pdf
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author Yu Zhang
Li Zhang
Zhen Wu
Jianping Tang
Xuan Wang
author_facet Yu Zhang
Li Zhang
Zhen Wu
Jianping Tang
Xuan Wang
author_sort Yu Zhang
collection DOAJ
description A male patient had suffered miscellaneous ocular symptoms for 20 years with auricular dysmorphosis and was diagnosed with Relapsing Polychondritis (RP) in the ear, nose, joints, and costal cartilage. The patient lost his vision owing to recurrent ocular symptoms for decades. He presented an increased IgA and was diagnosed with monoclonal gammopathy of undetermined significance (MGUS) and treated by prednisone and cyclophosphamide. His ocular symptoms relieved and serum IgA decreased after six months. In conclusion, RP is a systemic disease with a wide range of clinical symptoms and may lead to serious complications.
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spelling doaj.art-d5a956e46dc140f3a441ef072deda6842022-12-22T03:14:17ZengShiraz University of Medical SciencesIranian Journal of Immunology1735-13831735-367X2022-03-0119111011410.22034/iji.2022.91845.211048268Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case ReportYu Zhang0Li Zhang1Zhen Wu2Jianping Tang3Xuan Wang4Department of Rheumatology and Immunology, Tongji Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China.Department of Ophthalmology, Tongji Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China.Department of Rheumatology and Immunology, Tongji Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China.Department of Rheumatology and Immunology, Tongji Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China.Department of Rheumatology and Immunology, Tongji Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China.A male patient had suffered miscellaneous ocular symptoms for 20 years with auricular dysmorphosis and was diagnosed with Relapsing Polychondritis (RP) in the ear, nose, joints, and costal cartilage. The patient lost his vision owing to recurrent ocular symptoms for decades. He presented an increased IgA and was diagnosed with monoclonal gammopathy of undetermined significance (MGUS) and treated by prednisone and cyclophosphamide. His ocular symptoms relieved and serum IgA decreased after six months. In conclusion, RP is a systemic disease with a wide range of clinical symptoms and may lead to serious complications.https://iji.sums.ac.ir/article_48268_61e2d713bb7e2654e02cdc584966021f.pdfgammopathy of undetermined significancehematological malignanciesigamiscellaneous ocular symptoms, monoclonalrelapsing polychondritis
spellingShingle Yu Zhang
Li Zhang
Zhen Wu
Jianping Tang
Xuan Wang
Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case Report
Iranian Journal of Immunology
gammopathy of undetermined significance
hematological malignancies
iga
miscellaneous ocular symptoms, monoclonal
relapsing polychondritis
title Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case Report
title_full Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case Report
title_fullStr Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case Report
title_full_unstemmed Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case Report
title_short Relapsing Polychondritis Associated with Miscellaneous Ocular Symptoms and Increased IgA: a Case Report
title_sort relapsing polychondritis associated with miscellaneous ocular symptoms and increased iga a case report
topic gammopathy of undetermined significance
hematological malignancies
iga
miscellaneous ocular symptoms, monoclonal
relapsing polychondritis
url https://iji.sums.ac.ir/article_48268_61e2d713bb7e2654e02cdc584966021f.pdf
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AT zhenwu relapsingpolychondritisassociatedwithmiscellaneousocularsymptomsandincreasedigaacasereport
AT jianpingtang relapsingpolychondritisassociatedwithmiscellaneousocularsymptomsandincreasedigaacasereport
AT xuanwang relapsingpolychondritisassociatedwithmiscellaneousocularsymptomsandincreasedigaacasereport