The Gut Microbiota Is Associated with Clearance of <named-content content-type="genus-species">Clostridium difficile</named-content> Infection Independent of Adaptive Immunity

The Gut Microbiota Is Associated with Clearance of <named-content content-type="genus-species">Clostridium difficile</named-content> Infection Independent of Adaptive Immunity

ABSTRACT Clostridium (Clostridioides) difficile, a Gram-positive, anaerobic bacterium, is the leading single cause of nosocomial infections in the United States. A major risk factor for Clostridium difficile infection (CDI) is prior exposure to antibiotics, as they increase susceptibility to CDI by...

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Bibliographic Details
Main Authors: Jhansi L. Leslie, Kimberly C. Vendrov, Matthew L. Jenior, Vincent B. Young
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mSphere
Subjects:
Clostridium difficile
adaptive immunity
colonization resistance
intestinal colonization
microbiota
Online Access:https://journals.asm.org/doi/10.1128/mSphereDirect.00698-18

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